Rankin, N. J. , Burgess, K., Weidt, S., Wannamethee, G., Sattar, N. and Welsh, P. (2019) High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry. Annals of Clinical Biochemistry, 56(3), pp. 397-407. (doi: 10.1177/0004563219830432) (PMID:30832481) (PMCID:PMC6498755)

Welsh, P. et al. (2018) Circulating amino acids and the risk of macrovascular, microvascular, and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial. Diabetologia, 61(7), pp. 1581-1591. (doi: 10.1007/s00125-018-4619-x) (PMID:29728717) (PMCID:PMC6445481)

Delles, C. et al. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi: 10.1002/ejhf.1076) (PMID:29226610) (PMCID:PMC5947152)

Moore, D. A., Young, C. A., Morris, H. T. , Oien, K. A. , Lee, J. L., Jones, J. L. and Salto-Tellez, M. (2018) Time for change: a new training programme for morpho-molecular pathologists? Journal of Clinical Pathology, 71(4), pp. 285-290. (doi: 10.1136/jclinpath-2017-204821) (PMID:29113995) (PMCID:PMC5868526)

Grant, R. C. et al. (2018) Exome-wide association study of pancreatic cancer risk. Gastroenterology, 154(3), 719-722.e3. (doi: 10.1053/j.gastro.2017.10.015) (PMID:29074453) (PMCID:PMC5811358)

Wandy, J. , Zhu, Y., van der Hooft, J. J.J. , Daly, R. , Barrett, M. P. and Rogers, S. (2018) Ms2lda.org: web-based topic modelling for substructure discovery in mass spectrometry. Bioinformatics, 34(2), pp. 317-318. (doi: 10.1093/bioinformatics/btx582) (PMID:28968802) (PMCID:PMC5860206)

Dreyer, S.B., Jamieson, N.B. , Upstill-Goddard, R., Bailey, P.J. , McKay, C.J., Australian Pancreatic Cancer Genome Initiative, , Biankin, A.V. and Chang, D.K. (2018) Defining the molecular pathology of pancreatic body and tail adenocarcinom. British Journal of Surgery, 105(2), e183-e191. (doi: 10.1002/bjs.10772) (PMID:29341146) (PMCID:PMC5817249)

Alivernini, S., Gremese, E., McSharry, C., Tolusso, B., Ferraccioli, G., McInnes, I. B. and Kurowska-Stolarska, M. (2018) MicroRNA-155—at the critical interface of innate and adaptive immunity in arthritis. Frontiers in Immunology, 8, 1932. (doi: 10.3389/fimmu.2017.01932) (PMID:29354135) (PMCID:PMC5760508)

Grieve, E. , Hesselgreaves, H., Wu, O. , Chalkidou, K., Ruiz, F., Smith, P., Li, R., Morris, L. and Briggs, A. (2017) The Value of Health Technology Assessment: a mixed methods framework. F1000Research, 6, 2171. (doi: 10.7490/f1000research.1115169.1)

Gloaguen, Y. , Morton, F. , Daly, R. , Gurden, R., Rogers, S. , Wandy, J. , Wilson, D., Barrett, M. and Burgess, K. (2017) PiMP my metabolome: An integrated, web-based tool for LC-MS metabolomics data. Bioinformatics, 33(24), pp. 4007-4009. (doi: 10.1093/bioinformatics/btx499) (PMID:28961954) (PMCID:PMC5860087)

Cooke, S. L. et al. (2017) The driver mutational landscape of ovarian squamous cell carcinomas arising in mature cystic teratoma. Clinical Cancer Research, 23(24), pp. 7633-7640. (doi: 10.1158/1078-0432.CCR-17-1789) (PMID:28954785)

Jones, J. L., Oien, K. A. , Lee, J. L. and Salto-Tellez, M. (2017) Morphomolecular pathology: setting the framework for a new generation of pathologists. British Journal of Cancer, 117(11), pp. 1581-1582. (doi: 10.1038/bjc.2017.340) (PMID:29123262) (PMCID:PMC5729440)

Savoia, C., Volpe, M., Grassi, G., Borghi, C., Rosei, E. A. and Touyz, R. M. (2017) Personalized medicine—a modern approach for the diagnosis and management of hypertension. Clinical Science, 131(22), pp. 2671-2685. (doi: 10.1042/CS20160407) (PMID:29109301) (PMCID:PMC5736921)

Scott, P., Cornet, R., McCowan, C. and Peek, N. (2017) Addendum to Informatics for Health 2017: Advancing both science and practice. Journal of Innovation in Health Informatics, 24(3), pp. 291-310. (doi: 10.14236/jhi.v24i3.969) (PMID:29121853)

Scarpa, A. et al. (2017) Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours. Nature, 550(7677), p. 548. (doi: 10.1038/nature24026) (PMID:28953865)

Joshi, P. K. et al. (2017) Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nature Communications, 8, 910. (doi: 10.1038/s41467-017-00934-5) (PMID:29030599) (PMCID:PMC5715013)

Watts, A. E. et al. (2017) MicroRNA29a treatment improves early tendon injury. Molecular Therapy, 25(10), pp. 2415-2426. (doi: 10.1016/j.ymthe.2017.07.015) (PMID:28822690)

Jha, J.C. et al. (2017) NADPH oxidase-Nox5 accelerates renal injury in a mouse model of diabetic nephropathy. Journal of the American Society of Nephrology, 66(10), pp. 2691-2703. (doi: 10.2337/db16-1585) (PMID:28747378)

Rodie, M.E., Mudaliar, M.A.V. , Herzyk, P. , McMillan, M., Boroujerdi, M., Chudleigh, S., Tobias, E.S. and Ahmed, S.F. (2017) Androgen-responsive non-coding small RNAs extend the potential of HCG stimulation to act as a bioassay of androgen sufficiency. European Journal of Endocrinology, 177(4), pp. 339-346. (doi: 10.1530/EJE-17-0404) (PMID:28733293)

Nixon, R., Cerqueira, V., Kyriakou, A., Lucas-Herald, A. , McNeilly, J., McMillan, M., Purvis, A., Tobias, E.S. , McGowan, R. and Ahmed, S.F. (2017) Prevalence of endocrine and genetic abnormalities in boys evaluated systematically for a disorder of sex development. Human Reproduction, 32(10), pp. 2130-2137. (doi: 10.1093/humrep/dex280) (PMID:28938747) (PMCID:PMC5850224)

Kraja, A. T. et al. (2017) New blood pressure–associated loci identified in meta-analyses of 475 000 individuals. Circulation: Cardiovascular Genetics, 10(5), e001778. (doi: 10.1161/CIRCGENETICS.117.001778) (PMID:29030403)

Price, A. H., Weir, C. J., Welsh, P. , McLachlan, S., Strachan, M. W.J., Sattar, N. and Price, J. F. (2017) Comparison of non-traditional biomarkers, and combinations of biomarkers, for vascular risk prediction in people with type 2 diabetes: The Edinburgh Type 2 Diabetes Study. Atherosclerosis, 264, pp. 67-73. (doi: 10.1016/j.atherosclerosis.2017.07.009) (PMID:28777936) (PMCID:PMC5603967)

Raphael, B. J. et al. (2017) Integrated genomic characterization of pancreatic ductal adenocarcinoma. Cancer Cell, 32(2), 185-203.e13. (doi: 10.1016/j.ccell.2017.07.007) (PMID:28810144) (PMCID:PMC5964983)

Jenks, S. J., Conway, B. R., McLachlan, S., Teoh, W. L., Williamson, R. M., Webb, D. J., Welsh, P. , Sattar, N. , Strachan, M. W.J. and Price, J. F. (2017) Cardiovascular disease biomarkers are associated with declining renal function in type 2 diabetes. Diabetologia, 60(8), pp. 1400-1408. (doi: 10.1007/s00125-017-4297-0) (PMID:28528401) (PMCID:PMC5491560)

Zhang, Z.‐Y. et al. (2017) Novel urinary peptidomic classifier predicts incident heart failure. Journal of the American Heart Association, 6(8), e005432. (doi: 10.1161/JAHA.116.005432) (PMID:28784649) (PMCID:PMC5586413)

van der Hooft, J. J.J. , Wandy, J. , Young, F., Padmanabhan, S. , Gerasimidis, K. , Burgess, K. E.V., Barrett, M. P. and Rogers, S. (2017) Unsupervised discovery and comparison of structural families across multiple samples in untargeted metabolomics. Analytical Chemistry, 89(14), pp. 7569-7577. (doi: 10.1021/acs.analchem.7b01391) (PMID:28621528) (PMCID:PMC5524435)

Ohkuma, T. et al. (2017) Cardiac stress and inflammatory markers as predictors of heart failure in patients with type 2 diabetes: the ADVANCE trial. Diabetes Care, 40(9), pp. 1203-1209. (doi: 10.2337/dc17-0509) (PMID:28684396)

Wong, N. A.C.S., Adamczyk, L. A., Evans, S., Cullen, J., Oniscu, A. and Oien, K. A. (2017) A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma. Histopathology, 71(1), pp. 34-41. (doi: 10.1111/his.13194) (PMID:28226180)

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2017) Genomics of hypertension. Pharmacological Research, 121, pp. 219-229. (doi: 10.1016/j.phrs.2017.04.031) (PMID:28495658)

Kurowska-Stolarska, M. et al. (2017) MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. Nature Communications, 8, 15877. (doi: 10.1038/ncomms15877) (PMID:28639625) (PMCID:PMC5489689)

van den Berg, M. E. et al. (2017) Discovery of novel heart rate-associated loci using the Exome Chip. Human Molecular Genetics, 26(12), pp. 2346-2363. (doi: 10.1093/hmg/ddx113) (PMID:28379579) (PMCID:PMC5458336)

McInnes, I. B. and Schett, G. (2017) Pathogenetic insights from the treatment of rheumatoid arthritis. Lancet, 389(10086), pp. 2328-2337. (doi: 10.1016/S0140-6736(17)31472-1) (PMID:28612747)

McInnes, I. B. , Porter, D. and Siebert, S. (2017) Editorial: choosing new targets for rheumatoid arthritis therapeutics: too interesting to fail? Arthritis and Rheumatology, 69(6), pp. 1131-1134. (doi: 10.1002/art.40082) (PMID:28245351)

Babic, A. et al. (2017) Predictors of pretreatment CA125 at ovarian cancer diagnosis: a pooled analysis in the Ovarian Cancer Association Consortium. Cancer Causes and Control, 28(5), pp. 459-468. (doi: 10.1007/s10552-016-0841-3) (PMID:28050675) (PMCID:PMC5593071)

Johns, A. L. et al. (2017) Lost in translation: returning germline genetic results in genome-scale cancer research. Genome Medicine, 9, 41. (doi: 10.1186/s13073-017-0430-4) (PMID:28454591) (PMCID:PMC5408494)

Scott, P. J., Cornet, R., McCowan, C. , Peek, N., Fraccaro, P., Geifman, N., Gude, W. T., Hulme, W., Martin, G. P. and Williams, R. (2017) Informatics for Health 2017: Advancing both science and practice. Journal of Innovation in Health Informatics, 24(1), (doi: 10.14236/jhi.v24i1.939) (PMID:28665785)

Dreyer, S. B., Chang, D. K. , Bailey, P. and Biankin, A. V. (2017) Pancreatic cancer genomes: implications for clinical management and therapeutic development. Clinical Cancer Research, 23(7), pp. 1638-1646. (doi: 10.1158/1078-0432.CCR-16-2411) (PMID:28373362)

Dominiczak, A. , Delles, C. and Padmanabhan, S. (2017) Genomics and precision medicine for clinicians and scientists in hypertension. Hypertension, 69(4), e10-e13. (doi: 10.1161/HYPERTENSIONAHA.116.08252) (PMID:28193712)

Pishvaian, M. J., Biankin, A. V. , Bailey, P. , Chang, D. K. , Laheru, D., Wolfgang, C. L. and Brody, J. R. (2017) BRCA2 secondary mutation-mediated resistance to platinum and PARP inhibitor-based therapy in pancreatic cancer. British Journal of Cancer, 116, pp. 1021-1026. (doi: 10.1038/bjc.2017.40) (PMID:28291774)

Flynn, G. E., Withers, J. M., Macias, G., Sperling, J. R. , Henry, S. L., Cooper, J. M. , Burley, G. A. and Clark, A. W. (2017) Reversible DNA micro-patterning using the fluorous effect. Chemical Communications, 53(21), pp. 3094-3097. (doi: 10.1039/C7CC00288B) (PMID:28243661) (PMCID:PMC5358500)

Grieve, E. and Briggs, A. (2017) A Methodological Approach for Measuring the Impact of HTA. Technical Report. F1000Research. (doi: 10.7490/f1000research.1113738.1).

Scarpa, A. et al. (2017) Whole-genome landscape of pancreatic neuroendocrine tumours. Nature, 543(7643), pp. 65-71. (doi: 10.1038/nature21063) (PMID:28199314)

Maclay, J. D., Farley, J. M.B., McCowan, C. , Tweed, C. and Milroy, R. (2017) Obtaining tissue diagnosis in lung cancer patients with poor performance status and its influence on treatment and survival. Respiratory Medicine, 124, pp. 30-35. (doi: 10.1016/j.rmed.2017.01.002) (PMID:28284318)

Biankin, A. V. (2017) The road to precision oncology. Nature Genetics, 49(3), pp. 320-321. (doi: 10.1038/ng.3796) (PMID:28232728)

Firestein, G. S. and McInnes, I. B. (2017) Immunopathogenesis of rheumatoid arthritis. Immunity, 46(2), pp. 183-196. (doi: 10.1016/j.immuni.2017.02.006) (PMID:28228278) (PMCID:PMC5385708)

Siebert, S. , Porter, D., Paterson, C., Hampson, R., Gaya, D., Latosinska, A., Mischak, H., Schanstra, J., Mullen, W. and McInnes, I. (2017) Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups. Scientific Reports, 7, 40473. (doi: 10.1038/srep40473) (PMID:28091549) (PMCID:PMC5320079)

Al-Rawhani, M. A. et al. (2017) A colorimetric CMOS-based platform for rapid total serum cholesterol quantification. IEEE Sensors Journal, 17(2), pp. 240-247. (doi: 10.1109/JSEN.2016.2629018)

Salvi, E. et al. (2017) Genome-wide and gene-based meta-analyses identify novel loci influencing blood pressure response to hydrochlorothiazide. Hypertension, 69(1), pp. 51-59. (doi: 10.1161/HYPERTENSIONAHA.116.08267) (PMID:27802415) (PMCID:PMC5145728)

Cheah, B. C. , MacDonald, A. I., Barrett, M. P. and Cumming, D. R.S. (2017) Metabolomics on integrated circuit. Procedia Technology, 27, pp. 53-54. (doi: 10.1016/j.protcy.2017.04.025)

Liu, D. J. et al. (2017) Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics, 49, pp. 1758-1766. (doi: 10.1038/ng.3977) (PMID:29083408)

Preiss, D. and Sattar, N. (2016) Research digest: cardiac biomarkers for risk prediction. Lancet Diabetes and Endocrinology, 4(11), p. 890. (doi: 10.1016/S2213-8587(16)30293-5) (PMID:27743976)

Zhu, A. X. et al. (2016) Biomarker analyses of clinical outcomes in patients with advanced hepatocellular carcinoma treated with Sorafenib with or without Erlotinib in the SEARCH Trial. Clinical Cancer Research, 22(19), pp. 4870-4879. (doi: 10.1158/1078-0432.CCR-15-2883) (PMID:27220960)

Ehret, G. B. et al. (2016) The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics, 48(10), pp. 1171-1184. (doi: 10.1038/ng.3667) (PMID:27618452) (PMCID:PMC5042863)

Kar, S. P. et al. (2016) Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types. Cancer Discovery, 6(9), pp. 1052-1067. (doi: 10.1158/2159-8290.CD-15-1227) (PMID:27432226) (PMCID:PMC5010513)

Hoogendoorn, M. et al. (2016) Patient heterogeneity in health economic decision models for chronic obstructive pulmonary disease: are current models suitable to evaluate personalized medicine? Value in Health, 19(6), pp. 800-810. (doi: 10.1016/j.jval.2016.04.002) (PMID:27712708)

Van Der Hooft, J. , Padmanabhan, S. , Burgess, K. and Barrett, M. (2016) Erratum to: Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12(8), 139. (doi: 10.1007/s11306-016-1078-6)

Swanton, C. et al. (2016) Consensus on precision medicine for metastatic cancers: a report from the MAP conference. Annals of Oncology, 27(8), pp. 1443-1448. (doi: 10.1093/annonc/mdw192) (PMID:27143638)

McNeish, I. A. (2016) Prognostic pathways in early-stage ovarian cancer: can gene expression transcend histological subtype? Annals of Oncology, 27(8), pp. 1366-1368. (doi: 10.1093/annonc/mdw254) (PMID:27358384)

Van Der Hooft, J. J.J. , Padmanabhan, S. , Burgess, K. E.V. and Barrett, M. P. (2016) Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12, 125. (doi: 10.1007/s11306-016-1064-z) (PMID:27471437) (PMCID:PMC4932139)

Porter, D. et al. (2016) Tumour necrosis factor inhibition versus rituximab for patients with rheumatoid arthritis who require biological treatment (ORBIT): an open-label, randomised controlled, non-inferiority, trial. Lancet, 388(10041), pp. 239-247. (doi: 10.1016/S0140-6736(16)00380-9) (PMID:27197690)

Sattar, N. and Preiss, D. (2016) Diabetic microvascular complications as simple indicators of risk for cardiovascular outcomes and heart failure. Lancet Diabetes and Endocrinology, 4(7), pp. 555-556. (doi: 10.1016/s2213-8587(16)30097-3) (PMID:27216887)

Poortvliet, R. K.E. et al. (2016) Risk stratification and treatment effect of statins in secondary cardiovascular prevention in old age: additive value of N-terminal pro-B-type natriuretic peptide. European Journal of Preventive Cardiology, 23(10), pp. 1104-1113. (doi: 10.1177/2047487315617908) (PMID:26603744)

Cheah, B. C. , MacDonald, A. I., Martin, C., Streklas, A. J., Campbell, G., Al-Rawhani, M. A., Nemeth, B., Grant, J. P. , Barrett, M. P. and Cumming, D. R.S. (2016) An integrated circuit for chip-based analysis of enzyme kinetics and metabolite quantification. IEEE Transactions on Biomedical Circuits and Systems, 10(3), pp. 721-730. (doi: 10.1109/TBCAS.2015.2487603) (PMID:26742138)

Kleeff, J. et al. (2016) Pancreatic cancer. Nature Reviews Disease Primers, 2, 16022. (doi: 10.1038/nrdp.2016.22) (PMID:27158978)

Neisius, U. et al. (2016) Urine proteomics in the diagnosis of stable angina. BMC Cardiovascular Disorders, 16, 70. (doi: 10.1186/s12872-016-0246-y) (PMID:27095611) (PMCID:PMC483761)

Stitziel, N. O. et al. (2016) Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease. New England Journal of Medicine, 374(12), pp. 1134-1144. (doi: 10.1056/NEJMoa1507652) (PMID:26934567) (PMCID:PMC4850838)

Bailey, P. et al. (2016) Genomic analyses identify molecular subtypes of pancreatic cancer. Nature, 531(7592), pp. 47-52. (doi: 10.1038/nature16965) (PMID:26909576)

Rahbari, R. et al. (2016) Timing, rates and spectra of human germline mutation. Nature Genetics, 48(2), pp. 126-133. (doi: 10.1038/ng.3469) (PMID:26656846) (PMCID:PMC4731925)

Meeks, H. D. et al. (2016) BRCA2 polymorphic stop codon K3326X and the risk of breast, prostate, and ovarian cancers. Journal of the National Cancer Institute, 108(2), djv315. (doi: 10.1093/jnci/djv315) (PMID:26586665) (PMCID:PMC4907358)

Henry, S. L., Withers, J. M., Singh, I., Cooper, J. M. , Clark, A. W. , Burley, G. A. and Cogdell, R. J. (2016) DNA-directed spatial assembly of photosynthetic light-harvesting proteins. Organic and Biomolecular Chemistry, 14(4), pp. 1359-1362. (doi: 10.1039/c5ob02351c) (PMID:26660647)

Johnatty, S. E. et al. (2015) Genome-wide analysis identifies novel loci associated with ovarian cancer outcomes: findings from the Ovarian Cancer Association Consortium. Clinical Cancer Research, 21(23), pp. 5264-5276. (doi: 10.1158/1078-0432.CCR-15-0632) (PMID:26152742) (PMCID:PMC4624261)