The Value of Health Technology Assessment: a mixed methods framework

Grieve, E. , Hesselgreaves, H., Wu, O. , Chalkidou, K., Ruiz, F., Smith, P., Li, R., Morris, L. and Briggs, A. (2017) The Value of Health Technology Assessment: a mixed methods framework. F1000Research, 6, 2171. (doi: 10.7490/f1000research.1115169.1)

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Whilst much research has been undertaken on establishing what factors influence improved decision-making including good governance structures, expertise, political and institutional factors, resources and participation, how such influences on decision-making interact with local context and health systems, leading to impact on health outcomes, is less understood. The focus of our research is on the impact of Health Technology Assessment (HTA) as a tool for priority-setting with its explicit consideration of costs and benefits. Where evaluations have been undertaken, they mainly focus on processes or outcomes at the decision-making level, with impact on health outcomes rarely measured. Even in countries where HTA programmes are well established, evidence which identifies their outcomes and impact in terms of health gains is limited. For countries with greater capacity constraints, how decision-making interacts with ‘context’ leading to health outcomes is even less explored and arguably of critical importance. This research aims to provide a methodological framework and evidence base to: quantify the returns on investment in HTA; and produce explanatory programme theory that considers individual, interpersonal, institutional and systems-level components and their interactions on the mechanisms by which HTA impact can be optimised.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Grieve, Miss Eleanor and Briggs, Professor Andrew and Hesselgreaves, Dr Hannah and Wu, Professor Olivia
Authors: Grieve, E., Hesselgreaves, H., Wu, O., Chalkidou, K., Ruiz, F., Smith, P., Li, R., Morris, L., and Briggs, A.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Health Economics and Health Technology Assessment
Journal Name:F1000Research
Copyright Holders:Copyright © 2017 Grieve E et al.
First Published:First published in F1000Research 6:2171
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
690421Glasgow Molecular Pathology (GMP) NodeKarin OienMedical Research Council (MRC)MR/N005813/1ICS - EXPERIMENTAL THERAPEUTICS