Flynn, G. E., Withers, J. M., Macias, G., Sperling, J. R. , Henry, S. L., Cooper, J. M. , Burley, G. A. and Clark, A. W. (2017) Reversible DNA micro-patterning using the fluorous effect. Chemical Communications, 53(21), pp. 3094-3097. (doi: 10.1039/C7CC00288B) (PMID:28243661) (PMCID:PMC5358500)
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Abstract
We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Henry, Dr Sarah and Macias Sotuela, Dr Gerard and Burley, Dr Glenn and Flynn, Miss Gabriella and Cooper, Professor Jonathan and Clark, Professor Alasdair and Sperling, Dr Justin |
Authors: | Flynn, G. E., Withers, J. M., Macias, G., Sperling, J. R., Henry, S. L., Cooper, J. M., Burley, G. A., and Clark, A. W. |
College/School: | College of Science and Engineering > School of Chemistry College of Science and Engineering > School of Engineering College of Science and Engineering > School of Engineering > Biomedical Engineering |
Journal Name: | Chemical Communications |
Publisher: | Royal Society of Chemistry |
ISSN: | 1359-7345 |
ISSN (Online): | 1364-548X |
Published Online: | 23 February 2017 |
Copyright Holders: | Copyright © 2017 The Royal Society of Chemistry |
First Published: | First published in Chemical Communications 53(21): 3094-3097 |
Publisher Policy: | Reproduced under a Creative Commons License |
Data DOI: | 10.5525/gla.researchdata.380 |
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