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Amirkhah, R. et al. (2023) MmCMS: mouse models' consensus molecular subtypes of colorectal cancer. British Journal of Cancer, 128(7), pp. 1333-1343. (doi: 10.1038/s41416-023-02157-6) (PMID:36717674)

Edwards, S. C. et al. (2023) PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells. Journal of Experimental Medicine, 220(2), e20211431. (doi: 10.1084/jem.20211431) (PMID:36480166) (PMCID:PMC9732671)

Grocutt, L., Rutherford, A., Caldwell, D., Wilkinson, C., Chalmers, A.J. , Dempsey, L., Kelly, C. and O'Cathail, S.M. (2023) The impact of COVID-19 on radiotherapy services in Scotland, UK: a population-based study. Clinical Oncology, 35(2), e227-e234. (doi: 10.1016/j.clon.2022.11.018) (PMID:36528474) (PMCID:PMC9708615)

Rattigan, K., Zarou, M.-M. and Helgason, G. V. (2023) Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity. Blood Cells, Molecules, and Diseases, (doi: 10.1182/blood.2022018258) (PMID:36634302) (In Press)

Soloviev, D., Dzien, P., Mackintosh, A., Malviya, G., Brown, G. and Lewis, D. (2022) High molar activity [18F]tetrafluoroborate synthesis for sodium iodide symporter imaging by PET. EJNMMI Radiopharmacy and Chemistry, 7, 32. (doi: 10.1186/s41181-022-00185-w)

Cousins, A. et al. (2022) Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways. Leukemia, 36(12), pp. 2903-2907. (doi: 10.1038/s41375-022-01722-x) (PMID:36289348)

Fisher, N. C. et al. (2022) Biological misinterpretation of transcriptional signatures in tumour samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data. Clinical Cancer Research, 28(18), pp. 4056-4069. (doi: 10.1158/1078-0432.CCR-22-1102) (PMID:35792866) (PMCID:PMC9475248)

Devlin, L., Grocutt, L., Hunter, B., Chemu, H., Duffton, A., McDonald, A., Macleod, N., McLoone, P. and O'Cathail, S. M. (2022) The in-silico feasibility of dose escalated, hypofractionated radiotherapy for rectal cancer. Clinical and Translational Radiation Oncology, 36, pp. 24-30. (doi: 10.1016/j.ctro.2022.06.003) (PMID:35756193) (PMCID:PMC9218294)

Robertson, N. A. et al. (2022) Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects. Nature Medicine, 28(7), pp. 1439-1446. (doi: 10.1038/s41591-022-01883-3) (PMID:35788175) (PMCID:PMC9307482)

Kidger, A. M. et al. (2022) Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6. Oncogene, 41(20), pp. 2811-2823. (doi: 10.1038/s41388-022-02302-0) (PMID:35418690) (PMCID:PMC9106580)

Curio, S. et al. (2022) NKG2D signaling regulates IL-17A-producing γδT cells in mice to promote cancer progression. Discovery Immunology, 1(1), kyac002. (doi: 10.1093/discim/kyac002) (PMID:36277678) (PMCID:PMC9580227)

O'Cathail, S. M. , Wu, C.-H., Thomas, R., Hawkins, M. A., Maughan, T. S. and Lewis, A. (2021) NRF2 mediates therapeutic resistance to chemoradiation in colorectal cancer through a metabolic switch. Antioxidants, 10(9), 1380. (doi: 10.3390/antiox10091380)

Paterson, K., Zanivan, S. , Glasspool, R., Coffelt, S.B. and Zagnoni, M. (2021) Microfluidic technologies for immunotherapy studies on solid tumours. Lab on a Chip, 21(12), pp. 2306-2329. (doi: 10.1039/D0LC01305F) (PMID:34085677) (PMCID:PMC8204114)

Nielsen, S. R. et al. (2021) Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade. Nature Communications, 12, 3414. (doi: 10.1038/s41467-021-23731-7) (PMID:34099731) (PMCID:PMC8184753)

Zarou, M.-M., Vazquez, A. and Helgason, G. V. (2021) Folate metabolism: a re-emerging therapeutic target in haematological cancers. Leukemia, 35(6), pp. 1539-1551. (doi: 10.1038/s41375-021-01189-2) (PMID:33707653)

McFarlane, A. J., Fercoq, F., Coffelt, S. B. and Carlin, L. M. (2021) Neutrophil dynamics in the tumor microenvironment. Journal of Clinical Investigation, 131(6), e143759. (doi: 10.1172/JCI143759) (PMID:33720040)

Nacke, M. et al. (2021) An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism. Nature Communications, 12, 1623. (doi: 10.1038/s41467-021-21847-4) (PMID:33712589) (PMCID:PMC7955138)

Swaminathan, K., Campbell, A., Papalazarou, V., Jaber-Hijazi, F. , Nixon, C., McGhee, E., Strathdee, D., Sansom, O. J. and Machesky, L. M. (2021) The RAC1 target NCKAP1 plays a crucial role in the progression of Braf;Pten-driven melanoma in mice. Journal of Investigative Dermatology, 141(3), 628-637.e15. (doi: 10.1016/j.jid.2020.06.029) (PMID:32777214)

Alexander, P.G. et al. (2021) The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. British Journal of Cancer, 124, pp. 786-796. (doi: 10.1038/s41416-020-01168-x) (PMID:33223535)

Latif, A.-L. et al. (2021) BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature Communications, 12(1), 241. (doi: 10.1038/s41467-020-20378-8) (PMID:33431824) (PMCID:PMC7801601)

Edwards, S. C., Hoevenaar, W. H.M. and Coffelt, S. B. (2021) Emerging immunotherapies for metastasis. British Journal of Cancer, 124, pp. 37-48. (doi: 10.1038/s41416-020-01160-5) (PMID:33262520)

Coffelt, S. B. , Kabelitz, D., Silva-Santos, B., Kuball, J., Born, W. and Bank, I. (2020) Editorial: γδ T Cells in Cancer. Frontiers in Immunology, 11, 602411. (doi: 10.3389/fimmu.2020.602411) (PMID:33329597) (PMCID:PMC7714948)

Smith, T., O'Cathail, S. M. , Silverman, S., Robinson, M., Tsang, Y., Harrison, M. and Hawkins, M. A. (2020) Stereotactic Body Radiotherapy re-irradiation for locally recurrent rectal cancer: outcomes and toxicity. Advances in Radiation Oncology, 5(6), pp. 1311-1319. (doi: 10.1016/j.adro.2020.07.017) (PMID:33305093) (PMCID:PMC7718547)

Suzuki, T., Hayman, L., Kilbey, A., Edwards, J. and Coffelt, S. B. (2020) Gut γδ T cells as guardians, disruptors and instigators of cancer. Immunological Reviews, 298(1), pp. 198-217. (doi: 10.1111/imr.12916) (PMID:32840001)

O'Cathail, S. M. , Smith, T., Owens, R., Zeniou, A., Tsang, Y., Holyoake, D. L.P., Murray, L., Harrison, M. and Hawkins, M. A. (2020) Superior outcomes of nodal metastases compared to visceral sites in oligometastatic colorectal cancer treated with stereotactic ablative radiotherapy. Radiotherapy and Oncology, 151, pp. 280-286. (doi: 10.1016/j.radonc.2020.08.012) (PMID:32866563) (PMCID:PMC7689579)

O'Cathail, S. M. , Wu, C.-H., Lewis, A., Holmes, C., Hawkins, M. A. and Maughan, T. (2020) NRF2 metagene signature is a novel prognostic biomarker in colorectal cancer. Cancer Genetics, 248, pp. 1-10. (doi: 10.1016/j.cancergen.2020.08.006) (PMID:32871287)

Millar, R., Kilbey, A., Remak, S.-J., Severson, T. M., Dhayade, S., Sandilands, E., Foster, K., Bryant, D. M. , Blyth, K. and Coffelt, S. B. (2020) The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer. Molecular Oncology, 14(8), pp. 1868-1880. (doi: 10.1002/1878-0261.12734) (PMID:32484599) (PMCID:PMC7400785)

Muthalagu, N. et al. (2020) Repression of the type I interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in pancreatic ductal adenocarcinoma. Cancer Discovery, 10(6), pp. 872-887. (doi: 10.1158/2159-8290.CD-19-0620) (PMID:32200350) (PMCID:PMC7611248)

Brunton, H. et al. (2020) HNF4A and GATA6 loss reveals therapeutically actionable subtypes in pancreatic cancer. Cell Reports, 31(6), 107625. (doi: 10.1016/j.celrep.2020.107625) (PMID:32402285)

Hari, P. et al. (2019) The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype. Science Advances, 5(6), eaaw0254. (doi: 10.1126/sciadv.aaw0254) (PMID:31183403) (PMCID:PMC6551188)

This list was generated on Wed Mar 29 15:29:51 2023 BST.