Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways

Cousins, A. et al. (2022) Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways. Leukemia, 36(12), pp. 2903-2907. (doi: 10.1038/s41375-022-01722-x) (PMID:36289348)

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Abstract

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Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Bubnova, Xenia and Cousins, Dr Antony and Markert, Dr Elke and Halsey, Professor Chris and Herzyk, Dr Pawel and Tumanov, Dr Sergey and Manoharan, Dr Anand and Sumpton, Mr David and Olivares, Miss Orianne and Michie, Professor Alison and McGregor, Grace and Kamphorst, Dr Jurre
Authors: Cousins, A., Olivares, O., Markert, E., Manoharan, A., Bubnova, X., Bresolin, S., Degn, M., Li, Z., Silvestri, D., McGregor, G., Tumanov, S., Sumpton, D., Kamphorst, J. J., Michie, A. M., Herzyk, P., Valsecchi, M. G., Yeoh, A. E., Schmiegelow, K., te Kronnie, G., Gottlieb, E., and Halsey, C.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
College of Medical Veterinary and Life Sciences > School of Molecular Biosciences
Journal Name:Leukemia
Publisher:Springer Nature
ISSN:0887-6924
ISSN (Online):1476-5551
Published Online:26 October 2022
Copyright Holders:Copyright © 2022 The Authors
First Published:First published in Leukemia 36(12): 2903-2907
Publisher Policy:Reproduced under a Creative Commons licence

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
190794Identifying Novel Targets for eradication of acute lymphoblastic leukaemia in the central nervous systemChristina HalseyOffice of the Chief Scientific Adviser (CSO)ETM/374III - Immunology
190874CR-UK Centre renewalKaren VousdenNot Applicable (NA)C596/A18076Institute of Cancer Sciences
174115CRUK Centre RenewalOwen SansomCancer Research UK (CRUK)C7932/A25142CS - Beatson Institute for Cancer Research
170391The effect of tumour microenvironment on the metabolism of pancreatic cancer cellsJurre KamphorstCancer Research UK (CRUK)C50242/A17728CS - Beatson Institute for Cancer Research