Programmable active pixel sensor to investigate neural interactions within the retina

Hart, M.D., Prydderch, M.L., Morrison, J.D., Murdoch, D. and Mathieson, K. (2009) Programmable active pixel sensor to investigate neural interactions within the retina. Proceedings of the SPIE: The International Society for Optical Engineering, 7365, p. 736504. (doi: 10.1117/12.821624)

Abstract

Detection of the visual scene by the eye and the resultant neural interactions of the retina-brain system give us our perception of sight. We have developed an Active Pixel Sensor (APS) to be used as a tool for both furthering understanding of these interactions via experimentation with the retina and to make developments towards a realisable retinal prosthesis. The sensor consists of 469 pixels in a hexagonal array. The pixels are interconnected by a programmable neural network to mimic lateral interactions between retinal cells. Outputs from the sensor are in the form of biphasic current pulse trains suitable to stimulate retinal cells via a biocompatible array. The APS will be described with initial characterisation and test results.

• Item Type: Articles
• Additional Information: Copyright 2010 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Mathieson, Dr Keith and Morrison, Dr James
• Authors: Hart, M.D., Prydderch, M.L., Morrison, J.D., Murdoch, D., and Mathieson, K.
• Subjects: R Medicine > RE Ophthalmology
• College/School: College of Medical Veterinary and Life Sciences > School of Life Sciences
• Journal Name: Proceedings of the SPIE: The International Society for Optical Engineering
• Publisher: SPIE - The International Society for Optical Engineering
• ISSN: 0277-786X
• Published Online: 20 May 2009
• Copyright Holders: Copyright © 2009 SPIE
• First Published: First published in Proceedings of the SPIE - The International Society for Optical Engineering 7365:736504
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher