Goldie, F. C., Lee, M. M. Y. , Coats, C. J. and Nordin, S. (2024) Advances in multi-modality imaging in hypertrophic cardiomyopathy. Journal of Clinical Medicine, 13(3), 842. (doi: 10.3390/jcm13030842) (PMID:38337535) (PMCID:PMC10856479)
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Abstract
Hypertrophic cardiomyopathy (HCM) is characterized by abnormal growth of the myocardium with myofilament disarray and myocardial hyper-contractility, leading to left ventricular hypertrophy and fibrosis. Where culprit genes are identified, they typically relate to cardiomyocyte sarcomere structure and function. Multi-modality imaging plays a crucial role in the diagnosis, monitoring, and risk stratification of HCM, as well as in screening those at risk. Following the recent publication of the first European Society of Cardiology (ESC) cardiomyopathy guidelines, we build on previous reviews and explore the roles of electrocardiography, echocardiography, cardiac magnetic resonance (CMR), cardiac computed tomography (CT), and nuclear imaging. We examine each modality’s strengths along with their limitations in turn, and discuss how they can be used in isolation, or in combination, to facilitate a personalized approach to patient care, as well as providing key information and robust safety and efficacy evidence within new areas of research.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Coats, Dr Caroline and Lee, Matthew and Nordin, Dr Sabrina and Goldie, Dr Fraser |
| Creator Roles: | Goldie, F.Conceptualization, Writing – original draft, Writing – review and editing Nordin, S.Conceptualization, Writing – review and editing Lee, M.Conceptualization, Writing – original draft, Writing – review and editing Coats, C.Writing – review and editing |
| Authors: | Goldie, F. C., Lee, M. M. Y., Coats, C. J., and Nordin, S. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
| Journal Name: | Journal of Clinical Medicine |
| Publisher: | MDPI |
| ISSN: | 2077-0383 |
| ISSN (Online): | 2077-0383 |
| Copyright Holders: | Copyright © 2024 by the authors |
| First Published: | First published in Journal of Clinical Medicine 13(3):842 |
| Publisher Policy: | Reproduced under a Creative Commons licence |
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