Targeting helminths: the expanding world of type 2 immune effector mechanisms

Maizels, R. M. and Gause, W. C. (2023) Targeting helminths: the expanding world of type 2 immune effector mechanisms. Journal of Experimental Medicine, 220(10), e20221381. (doi: 10.1084/jem.20221381) (PMID:37638887) (PMCID:PMC10460967)

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Abstract

In this new review, Rick Maizels and Bill Gause summarize how type 2 immune responses combat helminth parasites through novel mechanisms, coordinating multiple innate and adaptive cell and molecular players that can eliminate infection and repair resultant tissue damage.

Item Type:Articles
Additional Information:In Special Collection: Cytokines Collection 2023.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Maizels, Professor Rick
Creator Roles:
Maizels, R.Conceptualization, Writing – original draft, Writing – review and editing
Authors: Maizels, R. M., and Gause, W. C.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:Journal of Experimental Medicine
Publisher:Rockefeller University Press
ISSN:0022-1007
ISSN (Online):1540-9538
Published Online:28 August 2023
Copyright Holders:Copyright © 2023 Maizels and Gause
First Published:First published in Journal of Experimental Medicine 220(10): e20221381
Publisher Policy:Reproduced under a creative commons licence

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
308411Molecular and Cellular Interactions in Helminth InfectionsRichard MaizelsWellcome Trust (WELLCOTR)219530/Z/19/ZSII - Parasitology
170547The Wellcome Centre for Molecular Parasitology ( Core Support )Andrew WatersWellcome Trust (WELLCOTR)104111/Z/14/ZSII - Parasitology