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White, M. P.J., Smyth, D. J. , Cook, L., Ziegler, S. F., Levings, M. K. and Maizels, R. M. (2021) The parasite cytokine mimic Hp-TGM potently replicates the regulatory effects of TGF-β on murine CD4+ T cells. Immunology and Cell Biology, (doi: 10.1111/imcb.12479) (In Press)

Carruthers, L. V. et al. (2021) Diminazene resistance in Trypanosoma congolense is not caused by reduced transport capacity but associated with reduced mitochondrial membrane potential. Molecular Microbiology, (doi: 10.1111/mmi.14733) (PMID:33932053) (Early Online Publication)

Biddau, M. et al. (2021) Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes. International Journal for Parasitology, 51(6), pp. 441-453. (doi: 10.1016/j.ijpara.2020.10.011) (PMID:33713652) (PMCID:PMC8126644)

Espada, C. R., Albuquerque-Wendt, A., Hornillos, V., Gluenz, E. , Coelho, A. C. and Uliana, S. R.B. (2021) Ros3 (Lem3p/CDC50) gene dosage is implicated in miltefosine susceptibility in Leishmania (Viannia) braziliensis clinical isolates and in Leishmania (Leishmania) major. ACS Infectious Diseases, 7(4), pp. 849-858. (doi: 10.1021/acsinfecdis.0c00857) (PMID:33724800) (PMCID:PMC8042657)

Annese, V. F. et al. (2021) A monolithic single-chip point-of-care platform for metabolomic prostate cancer detection. Microsystems and Nanoengineering, 7, 21. (doi: 10.1038/s41378-021-00243-4)

Milne, K. et al. (2021) Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum. eLife, 10, e62800. (doi: 10.7554/elife.62800) (PMID:33648633) (PMCID:PMC7924948)

Villafraz, O. et al. (2021) Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline. PLoS Pathogens, 17(3), e1009204. (doi: 10.1371/journal.ppat.1009204) (PMID:33647053) (PMCID:PMC7951978)

Cockram, P. E., Dickie, E. A., Barrett, M. P. and Smith, T. K. (2020) Halogenated tryptophan derivatives disrupt essential transamination mechanisms in bloodstream form Trypanosoma brucei. PLoS Neglected Tropical Diseases, 14(12), e0008928. (doi: 10.1371/journal.pntd.0008928) (PMID:33275612) (PMCID:PMC7744056)

Morang’a, C. M. et al. (2020) Machine learning approaches classify clinical malaria outcomes based on haematological parameters. BMC Medicine, 18, 375. (doi: 10.1186/s12916-020-01823-3) (PMID:33250058) (PMCID:PMC7702702)

Simwela, N., Stokes, B. H., Aghabi, D., Bogyo, M., Fidock, D. A. and Waters, A. (2020) Plasmodium berghei K13 mutations mediate in vivo artemisinin resistance that is reversed by proteasome inhibition. mBio, 11, e02312-20. (doi: 10.1128/mBio.02312-20) (PMID:33173001)

Giordani, F. et al. (2020) Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs. PLoS Pathogens, 16(11), e1008932. (doi: 10.1371/journal.ppat.1008932) (PMID:33141865) (PMCID:PMC7710103)

Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)

White, M. P., Johnston, C. J., Grainger, J. R., Konkel, J. E., O'Connor, R. A., Anderton, S. M. and Maizels, R. M. (2020) The helminth parasite Heligmosomoides polygyrus attenuates EAE in an IL-4Rα-dependent manner. Frontiers in Immunology, 11, 1830. (doi: 10.3389/fimmu.2020.01830)

Damasceno, J. D., Marques, C. A., Beraldi, D., Crouch, K. , Lapsley, C., Obonaga, R., Tosi, L. R.O. and McCulloch, R. (2020) Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication. eLife, 9, e58030. (doi: 10.7554/eLife.58030) (PMID:32897188) (PMCID:PMC7511235)

Drurey, C. , Coakley, G. and Maizels, R. M. (2020) Extracellular vesicles: new targets for vaccines against helminth parasites. International Journal for Parasitology, 50(9), pp. 623-633. (doi: 10.1016/j.ijpara.2020.04.011) (PMID:32659278)

Moxon, C. A. et al. (2020) Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria. Blood Advances, 4(13), pp. 2851-2864. (doi: 10.1182/bloodadvances.2019001258) (PMID:32579667) (PMCID:PMC7362376)

Damasceno, J. D., Reis-Cunha, J., Crouch, K. , Beraldi, D., Lapsley, C., Tosi, L. R.O., Bartholomeu, D. and McCulloch, R. (2020) Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication. PLoS Genetics, 16(7), e1008828. (doi: 10.1371/journal.pgen.1008828) (PMID:32609721) (PMCID:PMC7360064)

Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)

Simwela, N., Hughes, K. R., Roberts, A. B., Rennie, M. T., Barrett, M. P. and Waters, A. P. (2020) Experimentally engineered mutations in a ubiquitin hydrolase, UBP-1, modulate in vivo susceptibility to artemisinin and chloroquine in Plasmodium berghei. Antimicrobial Agents and Chemotherapy, 64(7), (doi: 10.1128/AAC.02484-19) (PMID:32340987) (PMCID:PMC7318008)

Doleželová, E., Kunzová, M., Dejung, M., Levin, M., Panicucci, B., Regnault, C., Janzen, C. J., Barrett, M. P. , Butter, F. and Zíková, A. (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei. PLoS Biology, 18(6), e3000741. (doi: 10.1371/journal.pbio.3000741) (PMID:32520929) (PMCID:PMC7307792)

Patil, H., Hughes, K. R., Lemgruber Soares, L. , Philip, N., Dickens, N. , Starnes, G. L. and Waters, A. P. (2020) Zygote morphogenesis but not the establishment of cell polarity in Plasmodium berghei is controlled by the small GTPase, RAB11A. PLoS Pathogens, 16(5), e1008091. (doi: 10.1371/journal.ppat.1008091) (PMID:32463831) (PMCID:PMC7255598)

Grazielle-Silva, V., Zeb, T. F., Machado, C. R., McCulloch, R. and Teixeira, S. M. R. (2020) Trypanosoma brucei and Trypanosoma cruzi DNA mismatch repair proteins act differently in the response to DNA damage caused by oxidative stress. Frontiers in Cellular and Infection Microbiology, 10, 154. (doi: 10.3389/fcimb.2020.00154) (PMID:32373549) (PMCID:PMC7176904)

Briggs, E. M., Marques, C. A., Reis-Cunha, J., Black, J., Campbell, S., Damasceno, J., Bartholomeu, D., Crouch, K. and McCulloch, R. (2020) Next-generation analysis of trypanosomatid genome stability and instability. In: Michels, P. A.M., Ginger, M. L. and Zilberstein, D. (eds.) Trypanosomatids: Methods and Protocols. Series: Methods in Molecular Biology (2116). Springer, pp. 225-262. ISBN 9781071602935 (doi:10.1007/978-1-0716-0294-2_15)

Dickie, E. A., Giordani, F. , Gould, M. K., Maeser, P., Burri, C., Mottram, J. C. , Rao, S. P.S. and Barrett, M. P. (2020) New drugs for human African trypanosomiasis:a twenty first century success story. Tropical Medicine and Infectious Disease, 5(1), 29. (doi: 10.3390/tropicalmed5010029) (PMID:32092897) (PMCID:PMC7157223)

Filbey, K. J. et al. (2019) Macrophage migration inhibitory factor (MIF) is essential for Type 2 effector cell immunity to an intestinal helminth parasite. Frontiers in Immunology, 10, 2375. (doi: 10.3389/fimmu.2019.02375) (PMID:31708913) (PMCID:PMC6821780)

Kovářová, J., Nagar, R., Faria, J., Ferguson, M. A.J., Barrett, M. P. and Horn, D. (2018) Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei. PLoS Pathogens, 14(12), e1007475. (doi: 10.1371/journal.ppat.1007475) (PMID:30589893) (PMCID:PMC6307712)

Almeida, L. V., Coqueiro-Dos-Santos, A., Rodriguez-Luiz, G. F., McCulloch, R. , Bartholomeu, D. C. and Reis-Cunha, J. L. (2018) Chromosomal copy number variation analysis by next generation sequencing confirms ploidy stability in Trypanosoma brucei subspecies. Microbial Genomics, 4(10), e000223. (doi: 10.1099/mgen.0.000223) (PMID:30256189) (PMCID:PMC6249438)

Rolot, M. et al. (2018) Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection. Nature Communications, 9, 4516. (doi: 10.1038/s41467-018-06978-5) (PMID:30375396) (PMCID:PMC6207712)

Matthews, K. R., McCulloch, R. and Morrison, L. J. (2015) The within-host dynamics of African trypanosome infections. Philosophical Transactions of the Royal Society B: Biological Sciences, 370(1675), 20140288. (doi: 10.1098/rstb.2014.0288) (PMID:26150654) (PMCID:PMC4528486)

This list was generated on Wed Jun 23 04:37:12 2021 BST.