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Briggs, E., Crouch, K. , Lemgruber Soares, L. , Hamilton, G., Lapsley, C. and McCulloch, R. (2019) Trypanosoma brucei ribonuclease H2A is an essential R-loop processing enzyme whose loss causes DNA damage during transcription initiation and antigenic variation. Nucleic Acids Research, (doi: 10.1093/nar/gkz644) (PMID:31350892) (PMCID:PMC6753483) (Early Online Publication)

Nenarokova, A., Záhonová, K., Krasilnikova, M., Gahura, O., McCulloch, R. , Zíková, A., Yurchenko, V. and Lukeš, J. (2019) Causes and effects of loss of classical non-homologous end joining pathway in parasitic eukaryotes. mBio, 10(4), e01541-9. (doi: 10.1128/mBio.01541-19) (PMID:31311886) (PMCID:PMC6635534)

Vieira Da Rocha, J.P., Passos-Silva, D.G., Mendes, I.C., Rocha, E.A., Gomes, D.A., Machado, C.R. and McCulloch, R. (2019) The DNA damage response is developmentally regulated in the African trypanosome. DNA Repair, 73, pp. 78-90. (doi: 10.1016/j.dnarep.2018.11.005) (PMID:30470509) (PMCID:PMC6329875)

Briggs, E., Hamilton, G., Crouch, K. , Lapsley, C. and McCulloch, R. (2018) Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome. Nucleic Acids Research, 46(22), pp. 11789-11805. (doi: 10.1093/nar/gky928) (PMID:30304482) (PMCID:PMC6294496)

Damasceno, J. D., Obonaga, R., Silva, G. L.A., Reis-Cunha, J. L., Duncan, S. M., Bartholomeu, D. C., Mottram, J. C. , McCulloch, R. and Tosi, L. R.O. (2018) Conditional genome engineering reveals canonical and divergent roles for the Hus1 component of the 9-1-1 complex in the maintenance of the plastic genome of Leishmania. Nucleic Acids Research, 46(22), pp. 11835-11846. (doi: 10.1093/nar/gky1017) (PMID:30380080) (PMCID:PMC6294564)

Briggs, E., Crouch, K. , Lemgruber, L. , Lapsley, C. and McCulloch, R. (2018) Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion. PLoS Genetics, 14(12), e1007729. (doi: 10.1371/journal.pgen.1007729) (PMID:30543624) (PMCID:PMC6292569)

Santos da Silva, M., Hovel-Miner, G. A., Briggs, E. M., Elias, M. C. and McCulloch, R. (2018) Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes. PLoS Pathogens, 14(11), e1007321. (doi: 10.1371/journal.ppat.1007321) (PMID:30440029) (PMCID:PMC6237402)

McCulloch, R. , Cobbold, C. A. , Figueiredo, L., Jackson, A., Morrison, L. J., Mugnier, M. R., Papavasiliou, N., Schnaufer, A. and Matthews, K. (2017) Emerging challenges in understanding trypanosome antigenic variation. Emerging Topics in Life Sciences, 1(6), pp. 585-592. (doi: 10.1042/ETLS20170104) (PMID:30271884) (PMCID:PMC6162063)

da Silva, M. S., Pavani, R. S., Damasceno, J. D., Marques, C. A. , McCulloch, R. , Tosi, L. R. O. and Elias, M. C. (2017) Nuclear DNA replication in trypanosomatids: there are no easy methods for solving difficult problems. Trends in Parasitology, 33(11), pp. 858-874. (doi: 10.1016/j.pt.2017.08.002) (PMID:28844718) (PMCID:PMC5662062)

This list was generated on Tue Oct 20 04:58:12 2020 BST.