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Havekes, R. et al. (2012) Gravin orchestrates protein kinase A and 2-adrenergic receptor signaling critical for synaptic plasticity and memory. Journal of Neuroscience, 32(50), pp. 18137-18149. (doi:10.1523/JNEUROSCI.3612-12.2012)

Edwards, H. V., Christian, F. and Baillie, G. S. (2012) cAMP: Novel concepts in compartmentalised signalling. Seminars in Cell and Developmental Biology, 23(2), pp. 181-190. (doi:10.1016/j.semcdb.2011.09.005)

Monterisi, S., Favia, M., Guerra, L., Cardone, R.A., Marzulli, D., Reshkin, S.J., Casavola, V. and Zaccolo, M. (2012) CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity. Journal of Cell Science, 125(5), pp. 1106-1117. (doi:10.1242/jcs.089086)

MacKenzie, K. F., Wallace, D. A., Hill, E. V., Anthony, D. F., Henderson, D. J.P., Houslay, D. M., Arthur, J. S. C., Baillie, G. S. and Houslay, M. D. (2011) Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation. Biochemical Journal, 435(3), pp. 755-769. (doi:10.1042/BJ20101184)

Sin, Y.Y., Edwards, H.V., Li, X., Day, J.P., Christian, F. , Dunlop, A.J., Adams, D.R., Zaccolo, M., Houslay, M.D. and Baillie, G.S. (2011) Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes. Journal of Molecular and Cellular Cardiology, 50(5), pp. 872-883. (doi:10.1016/j.yjmcc.2011.02.006) (PMID:21334344)

Day, J. P. et al. (2011) Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4). Journal of Medicinal Chemistry, 54(9), pp. 3331-3347. (doi:10.1021/jm200070e)

Anthony, D.F., Sin, Y.Y., Vadrevu, S., Advant, N., Day, J.P., Byrne, A.M., Lynch, M.J., Milligan, G. , Houslay, M.D. and Baillie, G.S. (2011) β-Arrestin 1 inhibits the GAP function of ARHGAP21 so as to promote the activation of RhoA following angiotensin II type 1A receptor stimulation. Molecular and Cellular Biology, 31(5), pp. 1066-1075. (doi:10.1128/MCB.00883-10) (PMID:21173159) (PMCID:PMC3067824)

Kim, H. W., Ha, S. H., Lee, M. N., Huston, E., Kim, D.-H., Jang, S. K., Suh, P.-G., Houslay, M. D. and Ryu, S. H. (2010) cAMP controls mTOR through regulation of the dynamic interaction between Rheb and Phosphodiesterase 4D. Molecular and Cellular Biology, 30(22), pp. 5406-5420. (doi:10.1128/MCB.00217-10)

Rampersad, S. N., Ovens, J. D., Huston, E., Umana, M. B., Wilson, L. S., Netherton, S. J., Lynch, M. J., Baillie, G. S. , Houslay, M. D. and Maurice, D. H. (2010) Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability. Journal of Biological Chemistry, 285(44), pp. 33614-33622. (doi:10.1074/jbc.M110.140004)

Christian, F. , Anthony, D. F., Vadrevu, S., Riddell, T., Day, J. P., McLeod, R., Adams, D. R., Baillie, G. S. and Houslay, M. D. (2010) p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways. Cellular Signalling, 22(10), pp. 1576-1596. (doi:10.1016/j.cellsig.2010.06.003)

Vaasa, A., Lust, M., Terrin, A., Uri, A. and Zaccolo, M. (2010) Small-molecule FRET probes for protein kinase activity monitoring in living cells. Biochemical and Biophysical Research Communications, 397(4), pp. 750-755. (doi:10.1016/j.bbrc.2010.06.026)

Li, X. et al. (2010) Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK. Biochemical Journal, 428(1), pp. 55-65. (doi:10.1042/BJ20091672)

Kelly, M. P. et al. (2010) Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes. Proceedings of the National Academy of Sciences of the United States of America, 107(18), pp. 8457-8462. (doi:10.1073/pnas.1000730107)

Bjorgo, E., Solheim, S. A., Abrahamsen, H., Baillie, G. S. , Brown, K. M., Berge, T., Okkenhaug, K., Houslay, M. D. and Tasken, K. (2010) Cross talk between phosphatidylinositol 3-kinase and cyclic AMP (cAMP)-protein kinase A signaling pathways at the level of a protein kinase B/β-Arrestin/cAMP phosphodiesterase 4 complex. Molecular and Cellular Biology, 30(7), pp. 1660-1672. (doi:10.1128/MCB.00696-09)

Houslay, M. D. (2010) Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown. Trends in Biochemical Sciences, 35(2), pp. 91-100. (doi:10.1016/j.tibs.2009.09.007)

Xu, T. et al. (2010) Inferring signaling pathway topologies from multiple perturbation measurements of specific biochemical species. Science Signaling, 3(113), ra20. (doi:10.1126/scisignal.2000517)

Vecsey, C. G. et al. (2009) Sleep deprivation impairs cAMP signalling in the hippocampus. Nature, 461(7267), pp. 1122-1125. (doi:10.1038/nature08488)

Kiely, P. A., Baillie, G. S. , Barrett, R., Buckley, D. A., Adams, D. R., Houslay, M. D. and O'Connor, R. (2009) Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for IGF-I-mediated regulation of focal adhesion kinase (FAK). Journal of Biological Chemistry, 284, pp. 20263-20274. (doi:10.1074/jbc.M109.017640) (PMID:19423701) (PMCID:PMC2740452)

Meng, D., Lynch, M. J., Huston, E., Beyermann, M., Eichhorst, J., Adams, D. R., Klusmann, E., Houslay, M. D. and Baillie, G. S. (2009) MEK1 binds directly to βArrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization. Journal of Biological Chemistry, 284(17), pp. 11425-11435. (doi:10.1074/jbc.M806395200) (PMID:19153083) (PMCID:PMC2670148)

Terrenoire, C., Houslay, M. D., Baillie, G. S. and Kass, R. S. (2009) The Cardiac IKs Potassium Channel Macromolecular Complex Includes the Phosphodiesterase PDE4D3. Journal of Biological Chemistry, 284(14), pp. 9140-9146. (doi:10.1074/jbc.M805366200)

McCahill, A., Campbell, L., McSorley, T., Lynch, M. J., Li, X., Yang, C., Baillie, G. S. , Houslay, M. D. and Sood, A. (2008) In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10). Cellular Signalling, 20(11), pp. 2071-2083. (doi:10.1016/j.cellsig.2008.07.017)

Mackenzie, K. F. et al. (2008) Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary change. Biochemical Journal, 411(2), pp. 361-369. (doi:10.1042/BJ20071251)

This list was generated on Tue Mar 19 19:43:00 2019 GMT.