Capoccia, M., Marconi, S., Avtaar Singh, S., Pisanelli, D. M. and De Lazzari, C. (2018) Simulation as a preoperative planning approach in advanced heart failure patients. A retrospective clinical analysis. BioMedical Engineering OnLine, 17(1), 52. (doi: 10.1186/s12938-018-0491-7) (PMID:29720187) (PMCID:PMC5930731)
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Abstract
Background: Modelling and simulation may become clinically applicable tools for detailed evaluation of the cardiovascular system and clinical decision-making to guide therapeutic intervention. Models based on pressure–volume relationship and zero-dimensional representation of the cardiovascular system may be a suitable choice given their simplicity and versatility. This approach has great potential for application in heart failure where the impact of left ventricular assist devices has played a significant role as a bridge to transplant and more recently as a long-term solution for non eligible candidates. Results: We sought to investigate the value of simulation in the context of three heart failure patients with a view to predict or guide further management. CARDIOSIM© was the software used for this purpose. The study was based on retrospective analysis of haemodynamic data previously discussed at a multidisciplinary meeting. The outcome of the simulations addressed the value of a more quantitative approach in the clinical decision process. Conclusions: Although previous experience, co-morbidities and the risk of potentially fatal complications play a role in clinical decision-making, patient-specific modelling may become a daily approach for selection and optimisation of device-based treatment for heart failure patients. Willingness to adopt this integrated approach may be the key to further progress.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Avtaar Singh, Sanjeet Singh |
| Authors: | Capoccia, M., Marconi, S., Avtaar Singh, S., Pisanelli, D. M., and De Lazzari, C. |
| College/School: | College of Medical Veterinary and Life Sciences |
| Journal Name: | BioMedical Engineering OnLine |
| Publisher: | BioMed Central |
| ISSN: | 1475-925X |
| Copyright Holders: | Copyright © 2018 The Authors |
| First Published: | First published in BioMedical Engineering OnLine 17(1):52 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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