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Bolognini, D. et al. (2019) Chemogenetics defines receptor-mediated functions of short chain free fatty acids. Nature Chemical Biology, 15(5), pp. 489-498. (doi: 10.1038/s41589-019-0270-1) (PMID:30992568)

Mancini, S., Mahmud, Z. A., Jenkins, L. , Bolognini, D., Newman, R., Barnes, M., Edye, M. E., McMahon, S. B., Tobin, A. B. and Milligan, G. (2019) On-target and off-target effects of novel orthosteric and allosteric activators of GPR84. Scientific Reports, 9, 1861. (doi: 10.1038/s41598-019-38539-1) (PMID:30755705) (PMCID:PMC6372602)

Hansen, A. H., Sergeev, E. , Bolognini, D., Sprenger, R. R., Ekberg, J. H., Ejsing, C. S., McKenzie, C. J., Rexen Ulven, E., Milligan, G. and Ulven, T. (2018) Discovery of a potent thiazolidine free fatty acid receptor 2 agonist with favorable pharmacokinetic properties. Journal of Medicinal Chemistry, 61(21), pp. 9534-9550. (doi: 10.1021/acs.jmedchem.8b00855) (PMID:30247908)

Milligan, G. (2018) G protein-coupled receptors not currently in the spotlight: free fatty acid receptor 2 and GPR35. British Journal of Pharmacology, 175(13), pp. 2543-2553. (doi: 10.1111/bph.14042) (PMID:28940377) (PMCID:PMC6003633)

Milligan, G. and Inoue, A. (2018) Genome editing provides new insights into receptor-controlled signalling pathways. Trends in Pharmacological Sciences, 39(5), pp. 481-493. (doi: 10.1016/ (PMID:29548548)

Sergeev, E. , Hansen, A. H., Bolognini, D., Kawakami, K., Kishi, T., Aoki, J., Ulven, T., Inoue, A., Hudson, B. D. and Milligan, G. (2017) A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias. Scientific Reports, 7, 13741. (doi: 10.1038/s41598-017-14096-3) (PMID:29061999) (PMCID:PMC5653858)

Milligan, G. , Shimpukade, B., Ulven, T. and Hudson, B. D. (2017) Complex pharmacology of free fatty acid receptors. Chemical Reviews, 117(1), pp. 67-110. (doi: 10.1021/acs.chemrev.6b00056) (PMID:27299848)

Bolognini, D. et al. (2016) A novel allosteric activator of free fatty acid 2 receptor displays unique Gi-functional bias. Journal of Biological Chemistry, 291, pp. 18915-18931. (doi: 10.1074/jbc.M116.736157) (PMID:27385588) (PMCID:PMC5009265)

Alvarez-Curto, E. and Milligan, G. (2016) Metabolism meets immunity: the role of free fatty acid receptors in the immune system. Biochemical Pharmacology, 114, pp. 3-13. (doi: 10.1016/j.bcp.2016.03.017) (PMID:27002183)

Sergeev, E. , Hansen, A. H., Pandey, S. K., MacKenzie, A. E., Hudson, B. D. , Ulven, T. and Milligan, G. (2016) Non-equivalence of key positively charged residues of the free fatty acid 2 receptor in the recognition and function of agonist versus antagonist ligands. Journal of Biological Chemistry, 291, pp. 303-317. (doi: 10.1074/jbc.M115.687939) (PMID:26518871) (PMCID:PMC4697166)

This list was generated on Sun Dec 10 18:04:59 2023 GMT.