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Zhou, J. et al. (2022) Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway. Cell Reports, 38(6), 110344. (doi: 10.1016/j.celrep.2022.110344) (PMID:35093235) (PMCID:PMC8768428)

Salas, J. H. et al. (2022) An antigenically diverse, representative panel of envelope glycoproteins for HCV vaccine development. Gastroenterology, 162(2), pp. 562-574. (doi: 10.1053/j.gastro.2021.10.005) (PMID:34655573) (PMCID:PMC8792218)

Sudhindar, P. D. et al. (2021) HCV activates somatic L1 retrotransposition–A potential hepatocarcinogenesis pathway. Cancers, 13(20), 5079. (PMCID:PMC8533982)

Sudhindar, P. D. et al. (2021) HCV activates somatic L1 retrotransposition—a potential hepatocarcinogenesis pathway. Cancers, 13(20), 5079. (doi: 10.3390/cancers13205079) (PMID:34680227) (PMCID:PMC8533982)

Szemiel, A. M. et al. (2021) In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2. PLoS Pathogens, 17(9), e1009929. (doi: 10.1371/journal.ppat.1009929) (PMID:34534263) (PMCID:PMC8496873)

Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)

Cowton, V. M. et al. (2021) Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design. npj Vaccines, 6, 7. (doi: 10.1038/s41541-020-00269-1) (PMID:33420102) (PMCID:PMC7794244)

Sanchez Velazquez, R. et al. (2020) Generation of a reporter yellow fever virus for high throughput antiviral assays. Antiviral Research, 183, 104939. (doi: 10.1016/j.antiviral.2020.104939) (PMID:32980446) (PMCID:PMC7649875)

Ansari, M. A. et al. (2019) Interferon lambda 4 impacts the genetic diversity of hepatitis C virus. eLife, 8, e42463. (doi: 10.7554/eLife.42463) (PMID:31478835) (PMCID:PMC6721795)

Magri, A., Mokrane, O., Lauder, K., Patel, A. H. and Castagnolo, D. (2019) Synthesis, biological evaluation and mode of action studies of novel amidinourea inhibitors of Hepatitis C Virus. Bioorganic and Medicinal Chemistry Letters, 29(5), pp. 724-728. (doi: 10.1016/j.bmcl.2019.01.008) (PMID:30661824)

Cowton, V. M., Singer, J. B., Gifford, R. J. and Patel, A. H. (2018) Predicting the effectiveness of hepatitis C virus neutralizing antibodies by bioinformatic analysis of conserved epitope residues using public sequence data. Frontiers in Immunology, 9, 1470. (doi: 10.3389/fimmu.2018.01470) (PMID:30013555) (PMCID:PMC6036255)

Krapchev, V. B., Rychłowska, M., Chmielewska, A., Zimmer, K., Patel, A. H. and Bieńkowska-Szewczyk, K. (2018) Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice. Virology, 519, pp. 33-41. (doi: 10.1016/j.virol.2018.03.026) (PMID:29631174) (PMCID:PMC5998380)

Meuleman, T. J., Dunlop, J. I., Owsianka, A. M., van de Langemheen, H., Patel, A. H. and Liskamp, R. M.J. (2018) Immobilization by surface conjugation of cyclic peptides for effective mimicry of the HCV-envelope E2 protein as a strategy toward synthetic vaccines. Bioconjugate Chemistry, 29(4), pp. 1091-1101. (doi: 10.1021/acs.bioconjchem.7b00755) (PMID:29382188)

Kumar, R., Singh, N., Abdin, M. Z., Patel, A. H. and Medigeshi, G. R. (2018) Dengue virus capsid interacts with DDX3X-a potential mechanism for suppression of antiviral functions in dengue infection. Frontiers in Cellular and Infection Microbiology, 7, 542. (doi: 10.3389/fcimb.2017.00542) (PMID:29387631) (PMCID:PMC5776122)

Desombere, I. et al. (2017) A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo. Antiviral Research, 148, pp. 53-64. (doi: 10.1016/j.antiviral.2017.10.015) (PMID:29074219) (PMCID:PMC5785094)

Naiyer, M. M. et al. (2017) KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C. Science Immunology, 2(15), eaal5296. (doi: 10.1126/sciimmunol.aal5296) (PMID:28916719)

Naik, A. S., Owsianka, A., Palmer, B. A., Halloran, C. J., Walsh, N., Crosbie, O., Kenny-Walsh, E., Patel, A. H. and Fanning, L. J. (2017) Reverse epitope mapping of the E2 glycoprotein in antibody associated hepatitis C virus. PLoS ONE, 12(5), e0175349. (doi: 10.1371/journal.pone.0175349) (PMID:28558001) (PMCID:PMC5448734)

Magri, A. et al. (2017) 17,β-estradiol inhibits hepatitis C virus mainly by interference with the release phase of its life cycle. Liver International, 37(5), pp. 669-677. (doi: 10.1111/liv.13303) (PMID:27885811) (PMCID:PMC5448036)

Vasiliauskaite, I. et al. (2017) Conformational flexibility in the immunoglobulin-like domain of the Hepatitis C Virus Glycoprotein E2. mBio, 8(3), e00382-17. (doi: 10.1128/mBio.00382-17) (PMID:28512091) (PMCID:PMC5433095)

Heerman van Voss, M. R. et al. (2017) Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer. OncoTargets and Therapy, 10, pp. 3501-3513. (doi: 10.2147/OTT.S140639) (PMID:28761359) (PMCID:PMC5522823)

Cowton, V. M., Angus, A. G.N., Cole, S. J., Markopoulou, C. K., Owsianka, A., Dunlop, J. I., Gardner, D., Krey, T. and Patel, A. H. (2016) Role of conserved E2 residue W420 in receptor binding and hepatitis C virus infection. Journal of Virology, 90(16), pp. 7456-7468. (doi: 10.1128/JVI.00685-16) (PMID:27279607) (PMCID:PMC4984626)

Swann, R.E. , Mandalou, P., Robinson, M.W., Ow, M.M., Foung, S.K.H., McLauchlan, J. , Patel, A.H. and Cramp, M.E. (2016) Anti-envelope antibody responses in individuals at high risk of hepatitis C virus who resist infection. Journal of Viral Hepatitis, 23(11), pp. 873-880. (doi: 10.1111/jvh.12568) (PMID:27405885) (PMCID:PMC5244678)

Magri, A., Ozerov, A. A., Tunitskaya, V. L., Valuev-Elliston, V. T., Wahid, A., Pirisi, M., Simmonds, P., Ivanov, A. V., Novikov, M. S. and Patel, A. H. (2016) Exploration of acetanilide derivatives of 1-(ω-phenoxyalkyl)uracils as novel inhibitors of Hepatitis C Virus replication. Scientific Reports, 6, 29487. (doi: 10.1038/srep29487) (PMID:27406141) (PMCID:PMC4942610)

Swann, R. E. , Cowton, V. M., Robinson, M. W., Cole, S. J., Barclay, S. T., Mills, P. R., Thomson, E. C. , McLauchlan, J. and Patel, A. (2016) Broad anti-hepatitis C virus (HCV) antibody responses are associated with improved clinical disease parameters in chronic HCV infection. Journal of Virology, 90(9), pp. 4530-4543. (doi: 10.1128/JVI.02669-15) (PMID:26912610) (PMCID:PMC4836347)

Robinson, M. W., Hughes, J. , Wilkie, G. S., Swann, R. , Barclay, S. T., Mills, P. R., Patel, A. H. , Thomson, E. C. and McLauchlan, J. (2016) Tracking TCRß sequence clonotype expansions during antiviral therapy using high-throughput sequencing of the hypervariable region. Frontiers in Immunology, 7, 131. (doi: 10.3389/fimmu.2016.00131) (PMID:27092143) (PMCID:PMC4820669)

Sandomenico, A. et al. (2016) Generation and characterization of monoclonal antibodies against a cyclic variant of Hepatitis C Virus E2 epitope 412-422. Journal of Virology, 90(7), pp. 3745-3759. (doi: 10.1128/JVI.02397-15) (PMID:26819303) (PMCID:PMC4794675)

Dunlop, J., Owsianka, A., Cowton, V. and Patel, A. (2015) Current and future prophylactic vaccines for hepatitis C virus. Vaccine: Development and Therapy, 2015(5), pp. 31-44. (doi: 10.2147/VDT.S48437)

Robinson, M.W., Swann, R. , Sigruener, A., Barclay, S.T., Mills, P.R., McLauchlan, J. and Patel, A. H. (2015) Elevated interferon-stimulated gene transcription in peripheral blood mononuclear cells occurs in patients infected with genotype 1 but not genotype 3 hepatitis C virus. Journal of Viral Hepatitis, 22(4), pp. 384-390. (doi: 10.1111/jvh.12310) (PMID:25200131) (PMCID:PMC4409080)

Zhou, X., Sun, P., Lucendo-Villarin, B., Angus, A. G.N., Szkolnicka, D., Cameron, K., Farnworth, S. L., Patel, A. H. and Hay, D. C. (2014) Modulating innate immunity improves Hepatitis C virus infection and replication in stem cell-derived hepatocytes. Stem Cell Reports, 3(1), pp. 204-214. (doi: 10.1016/j.stemcr.2014.04.018) (PMID:25068132) (PMCID:PMC4110790)

Xiao, F. et al. (2014) Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents. PLoS Pathogens, 10(5), e1004128. (doi: 10.1371/journal.ppat.1004128) (PMID:24830295) (PMCID:PMC4022730)

Keck, Z.-y., Angus, A. G.N., Wang, W., Lau, P., Wang, Y., Gatherer, D., Patel, A. H. and Foung, S. K.H. (2014) Non-random escape pathways from a broadly neutralizing human monoclonal antibody map to a highly conserved region on the hepatitis c virus E2 glycoprotein encompassing amino acids 412–423. PLoS Pathogens, 10(8), e1004297. (doi: 10.1371/journal.ppat.1004297) (PMID:25122476) (PMCID:PMC4133389)

Robinson, M. W., McGuinness, D., Swann, R. , Barclay, S., Mills, P. R., Patel, A. H. , McLauchlan, J. and Shiels, P. G. (2013) Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease. Aging Cell, 12(6), pp. 1141-1143. (doi: 10.1111/acel.12125) (PMID:23931242)

Sun, P., Zhou, X., Farnworth, S.L., Patel, A.H. and Hay, D.C. (2013) Modeling human liver biology using stem cell-derived hepatocytes. International Journal of Molecular Sciences, 14(11), pp. 22011-22021. (doi: 10.3390/ijms141122011) (PMID:24201130) (PMCID:PMC3856048)

Bol, G.M., Raman, V., van der Groep, P., Vermeulen, J.F., Patel, A.H. , van der Wall, E. and van Diest, P.J. (2013) Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer. PLoS ONE, 8(5), e63548. (doi: 10.1371/journal.pone.0063548) (PMID:23696831) (PMCID:PMC3656050)

This list was generated on Mon Dec 4 19:55:47 2023 GMT.