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Witkowska McConnell, W. et al. (2021) Paper microfluidic implementation of loop mediated isothermal amplification for early diagnosis of hepatitis C virus. Nature Communications, 12, 6994. (doi: 10.1038/s41467-021-27076-z) (PMID:34848705) (PMCID:PMC8632961)

Guo, C., Reuss, D., Coey, J. D., Sukumar, S., Lang, B., McLauchlan, J. , Boulant, S., Stanifer, M. L. and Bamford, C. G. G. (2021) Conserved induction of distinct antiviral signalling kinetics by primate interferon lambda 4 proteins. Frontiers in Immunology, 12, 772588. (doi: 10.3389/fimmu.2021.772588)

Bamford, C. G.G. and McLauchlan, J. (2021) An interferon lambda 4-associated variant in the hepatitis C virus RNA polymerase affects viral replication in infected cells. Journal of General Virology, 102(2), 001495. (doi: 10.1099/jgv.0.001495) (PMID:32897180)

Davis, C. et al. (2020) Postexposure prophylaxis with rVSV-ZEBOV following exposure to a patient with Ebola virus disease relapse in the United Kingdom: an operational, safety, and immunogenicity report. Clinical Infectious Diseases, 71(11), pp. 2872-2879. (doi: 10.1093/cid/ciz1165) (PMID:31784751) (PMCID:PMC7778350)

Guzik, T. J. et al. (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research, 116(10), pp. 1666-1687. (doi: 10.1093/cvr/cvaa106) (PMID:32352535) (PMCID:PMC7197627)

Childs, K. et al. (2019) Suboptimal SVR rates in African patients with atypical Genotype 1 subtypes: implications for global elimination of Hepatitis C. Journal of Hepatology, 71(6), pp. 1099-1105. (doi: 10.1016/j.jhep.2019.07.025) (PMID:31400349)

Jerome, H. et al. (2019) Metagenomic next-generation sequencing aids the diagnosis of viral infections in febrile returning travellers. Journal of Infection, 79(4), pp. 383-388. (doi: 10.1016/j.jinf.2019.08.003) (PMID:31398374) (PMCID:PMC6859916)

Wing, P. A.C. et al. (2019) Amino acid substitutions in genotype 3a hepatitis C virus polymerase protein affect responses to sofosbuvir. Gastroenterology, 157(3), 692-704.e9. (doi: 10.1053/j.gastro.2019.05.007) (PMID:31078622)

Davis, C. et al. (2019) New highly diverse hepatitis C strains detected in sub‐Saharan Africa have unknown susceptibility to direct‐acting antiviral treatments. Hepatology, 69(4), pp. 1426-1441. (doi: 10.1002/hep.30342) (PMID:30387174) (PMCID:PMC6492010)

Bamford, C. G.G. and McLauchlan, J. (2019) Comparative host genomics: how has human evolution affected our immune defence against hepatitis C virus? Future Virology, 14(3), pp. 125-128. (doi: 10.2217/fvl-2019-0017)

Xu, R. et al. (2019) HCV genotype 6 prevalence, spontaneous clearance and diversity amongst elderly members of the Li ethnic minority in Baisha County, China. Journal of Viral Hepatitis, 26(5), pp. 529-540. (doi: 10.1111/jvh.13062) (PMID:30629794)

Singer, J. B., Thomson, E. C. , McLauchlan, J. , Hughes, J. and Gifford, R. J. (2018) GLUE: a flexible software system for virus sequence data. BMC Bioinformatics, 19, 532. (doi: 10.1186/s12859-018-2459-9) (PMID:30563445) (PMCID:PMC6299651)

Zhu, H., Gifford, R. and Murcia, P. R. (2018) Distribution, diversity and evolution of endogenous retroviruses in perissodactyl genomes. Journal of Virology, 92(23), e00927-18. (doi: 10.1128/JVI.00927-18) (PMID:30209175) (PMCID:PMC6232481)

Nickbakhsh, S. , McLauchlan, J. and Leitch, E. C. M. (2018) Evaluating “treatment as prevention” on the road to hepatitis C virus elimination. Annals of Blood, 3, 44. (doi: 10.21037/aob.2018.10.05)

Bamford, C. G.G. et al. (2018) A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages. PLoS Pathogens, 14(10), e1007307. (doi: 10.1371/journal.ppat.1007307) (PMID:30308076) (PMCID:PMC6181419)

Karamitros, T. et al. (2018) Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model. Proceedings of the National Academy of Sciences of the United States of America, 115(41), pp. 10434-10439. (doi: 10.1073/pnas.1811940115) (PMID:30249655) (PMCID:PMC6187174)

López-Camacho, C. et al. (2018) Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors. Nature Communications, 9, 2441. (doi: 10.1038/s41467-018-04859-5) (PMID:29934593) (PMCID:PMC6015009)

da Silva Filipe, A. et al. (2018) Reply to: "Reply to: 'Response to DAA therapy in the NHS England Early Access Programme for rare HCV subtypes from low and middle income countries'". Journal of Hepatology, 68(4), pp. 864-866. (doi: 10.1016/j.jhep.2017.11.044) (PMID:29339112)

Dickson, L. B. et al. (2018) Diverse laboratory colonies of Aedes aegypti harbor the same adult midgut bacterial microbiome. Parasites and Vectors, 11, 207. (doi: 10.1186/s13071-018-2780-1) (PMID:29587819) (PMCID:PMC587006)

Zmurko, J., Vasey, D. B., Donald, C. L. , Armstrong, A. A., McKee, M. L., Kohl, A. and Clayton, R. F. (2018) Mitigating the risk of Zika virus contamination of raw materials and cell lines in the manufacture of biologicals. Journal of General Virology, 99, pp. 219-229. (doi: 10.1099/jgv.0.000995) (PMID:29239715) (PMCID:PMC5882083)

da Silva Filipe, A. et al. (2017) Response to DAA therapy in the NHS England early access programme for rare HCV subtypes from low and middle income countries. Journal of Hepatology, 67(6), pp. 1348-1350. (doi: 10.1016/j.jhep.2017.06.035) (PMID:28789880)

Ansari, M. A. et al. (2017) Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus. Nature Genetics, 49(5), pp. 666-673. (doi: 10.1038/ng.3835) (PMID:28394351)

de Souza, W. M., Romeiro, M. F., Modha, S. , de Araujo, J., Queiroz, L. H., Durigon, E. L., Moraes Figueiredo, L. T., Murcia, P. R. and Gifford, R. (2017) Chapparvoviruses occur in at least three vertebrate classes and have a broad biogeographic distribution. Journal of General Virology, 98(2), pp. 225-229. (doi: 10.1099/jgv.0.000671) (PMID:28284244) (PMCID:PMC5646239)

Mottram, T. J., Li, P. , Dietrich, I., Shi, X. , Brennan, B. , Varjak, M. and Kohl, A. (2017) Mutational analysis of Rift Valley fever phlebovirus nucleocapsid protein indicates novel conserved, functional amino acids. PLoS Neglected Tropical Diseases, 11(12), e0006155. (doi: 10.1371/journal.pntd.0006155) (PMID:29267287) (PMCID:PMC5764413)

Schnettler, E., Sreenu, V. B. , Mottram, T. and McFarlane, M. (2016) Wolbachia restricts insect specific flavivirus infection in Aedes aegypti cells. Journal of General Virology, 97(11), pp. 3024-3029. (doi: 10.1099/jgv.0.000617) (PMID:27692043) (PMCID:PMC5120408)

McNaughton, A. L., Cameron, I. D., Wignall-Fleming, E. B., Biek, R. , McLauchlan, J. , Gunson, R. N., Templeton, K., Tan, H. M.-L. and McWilliam Leitch, E. C. (2015) Spatiotemporal reconstruction of the introduction of hepatitis C virus into Scotland and its subsequent regional transmission. Journal of Virology, 89(22), pp. 11223-11232. (doi: 10.1128/JVI.02106-15) (PMID:26311892) (PMCID:PMC4645645)

Robinson, M. W. et al. (2015) Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection. Liver International, 35(10), pp. 2256-2264. (doi: 10.1111/liv.12830) (PMID:25800823) (PMCID:PMC4949513)

Robinson, M. W., McGuinness, D., Swann, R. , Barclay, S., Mills, P. R., Patel, A. H. , McLauchlan, J. and Shiels, P. G. (2013) Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease. Aging Cell, 12(6), pp. 1141-1143. (doi: 10.1111/acel.12125) (PMID:23931242)

McWilliam Leitch, E. C. and McLauchlan, J. (2013) Determining the cellular diversity of hepatitis C virus quasispecies by single-cell viral sequencing. Journal of Virology, 87(23), pp. 12648-12655. (doi: 10.1128/JVI.01602-13) (PMID:24049174) (PMCID:PMC3838117)

Mazumder, N. et al. (2013) Fluorescence lifetime imaging of alterations to cellular metabolism by domain 2 of the Hepatitis C virus core protein. PLoS ONE, 8(6), e66738. (doi: 10.1371/journal.pone.0066738) (PMID:23826122) (PMCID:PMC3691201)

Herod, M. R., Jones, D. M., McLauchlan, J. and McCormick, C. J. (2012) Increasing rate of cleavage at boundary between non-structural proteins 4B and 5A inhibits replication of Hepatitis C virus. Journal of Biological Chemistry, 287(1), pp. 568-580. (doi: 10.1074/jbc.M111.311407) (PMID:22084249) (PMCID:PMC3249110)

Felmlee, D. J. et al. (2010) Intravascular transfer contributes to postprandial increase in numbers of very-low-density hepatitis C virus particles. Gastroenterology, 139(5), pp. 1774-1783. (doi: 10.1053/j.gastro.2010.07.047) (PMID:20682323)

Jones, D.M., Domingues, P., Targett-Adams, P. and McLauchlan, J. (2010) Comparison of U2OS and Huh-7 cells for identifying host factors that affect hepatitis C virus RNA replication. Journal of General Virology, 91(9), pp. 2238-2248. (doi: 10.1099/vir.0.022210-0) (PMID:20505011)

Benga, W. J. A. et al. (2010) Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles. Hepatology, 51(1), pp. 43-53. (doi: 10.1002/hep.23278) (PMID:20014138)

Angus, A.G.N. et al. (2010) Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein. Journal of General Virology, 91(1), pp. 122-132. (doi: 10.1099/vir.0.015909-0) (PMID:19793905) (PMCID:PMC2885062)

Targett-Adams, P., Boulant, S., Douglas, M. W. and McLauchlan, J. (2010) Lipid metabolism and HCV infection. Viruses, 2(5), pp. 1195-1217. (doi: 10.3390/v2051195) (PMID:21994676) (PMCID:PMC3187597)

Tang, X., Wagoner, J., Negash, A., Austin, M., McLauchlan, J. , Hahn, Y. S., Rosen, H. R. and Polyak, S. J. (2010) Functional characterization of core genes from patients with acute hepatitis C virus infection. Journal of Infectious Diseases, 201(6), pp. 912-922. (doi: 10.1086/650699) (PMID:20170366) (PMCID:PMC2827820)

Jones, D.M. and McLauchlan, J. (2010) Hepatitis C virus: assembly and release of virus particles. Journal of Biological Chemistry, 285(30), pp. 22733-22739. (doi: 10.1074/jbc.R110.133017) (PMID:20457608) (PMCID:PMC2906262)

McLauchlan, J. (2009) Hepatitis C virus: viral proteins on the move. Biochemical Society Transactions, 37(5), p. 986. (doi: 10.1042/BST0370986) (PMID:19754437)

McLauchlan, J. (2009) Lipid droplets and hepatitis C virus infection. Biochimica et Biophysica Acta: Molecular and Cell Biology of Lipids, 1791(6), pp. 552-559. (doi: 10.1016/j.bbalip.2008.12.012) (PMID:19167518)

Jones, D. M., Patel, A. H., Targett-Adams, P. and McLauchlan, J. (2009) The hepatitis c virus ns4b protein can trans-complement viral rna replication and modulates production of infectious virus. Journal of Virology, 83(5), pp. 2163-2177. (doi: 10.1128/JVI.01885-08) (PMID:19073716) (PMCID:PMC2643717)

Ratinier, M., Boulant, S., Crussard, S., McLauchlan, J. and Lavergne, J.-P. (2009) Subcellular localizations of the hepatitis C virus alternate reading frame proteins. Virus Research, 139(1), pp. 106-110. (doi: 10.1016/j.virusres.2008.09.011) (PMID:18996421)

Roohvand, F. et al. (2009) Initiation of hepatitis C virus infection requires the dynamic microtubule network: role of the viral nucleocapsid protein. Journal of Biological Chemistry, 284(20), pp. 13778-13791. (doi: 10.1074/jbc.M807873200) (PMID:19269968) (PMCID:PMC2679479)

Ratinier, M., Boulant, S., Combet, C., Targett-Adams, P., McLauchlan, J. and Lavergne, J.-P. (2008) Transcriptional slippage prompts recoding in alternate reading frames in the hepatitis C virus (HCV) core sequence from strain HCV-1. Journal of General Virology, 89(7), pp. 1569-1578. (doi: 10.1099/vir.0.83614-0) (PMID:18559926)

Boulant, S., Douglas, M.W., Moody, L., Budkowska, A., Targett-Adams, P. and McLauchlan, J. (2008) Hepatitis C virus core protein induces lipid droplet redistribution in a microtubule- and dynein-dependent manner. Traffic, 9(8), pp. 1268-1282. (doi: 10.1111/j.1600-0854.2008.00767.x) (PMID:18489704)

Targett-Adams, P., Boulant, S. and McLauchlan, J. (2008) Visualization of double-stranded RNA in cells supporting hepatitis C virus RNA replication. Journal of Virology, 82(5), pp. 2182-2195. (doi: 10.1128/JVI.01565-07) (PMID:18094154) (PMCID:PMC2258944)

Targett-Adams, P., Hope, G., Boulant, S. and McLauchlan, J. (2008) Maturation of hepatitis C virus core protein by signal peptide peptidase is required for virus production. Journal of Biological Chemistry, 283(24), pp. 16850-16859. (doi: 10.1074/jbc.M802273200) (PMID:18424431)

Shavinskaya, A., Boulant, S., Penin, F., McLauchlan, J. and Bartenschlager, R. (2007) The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly. Journal of Biological Chemistry, 282(51), pp. 37158-37169. (doi: 10.1074/jbc.M707329200) (PMID:17942391)

Boulant, S., Targett-Adams, P. and McLauchlan, J. (2007) Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus. Journal of General Virology, 88(8), pp. 2204-2213. (doi: 10.1099/vir.0.82898-0) (PMID:17622624)

Jones, D.M., Gretton, S.N., McLauchlan, J. and Targett-Adams, P. (2007) Mobility analysis of an NS5A-GFP fusion protein in cells actively replicating hepatitis C virus subgenomic RNA. Journal of General Virology, 88(2), pp. 470-475. (doi: 10.1099/vir.0.82363-0) (PMID:17251564)

Boulant, S., Montserret, R., Hope, R. G., Ratinier, M., Targett-Adams, P., Lavergne, J.-P., Penin, F. and McLauchlan, J. (2006) Structural determinants that target the hepatitis C virus core protein to lipid droplets. Journal of Biological Chemistry, 281(31), pp. 22236-22247. (doi: 10.1074/jbc.M601031200) (PMID:16704979)

Hope, R.G., McElwee, M.J. and McLauchlan, J. (2006) Efficient cleavage by signal peptide peptidase requires residues within the signal peptide between the core and E1 proteins of hepatitis C virus strain J1. Journal of General Virology, 87(3), pp. 623-627. (doi: 10.1099/vir.0.81371-0) (PMID:16476983)

Targett-Adams, P., Schaller, T., Hope, R.G., Lanford, R.E., Lemon, S.M., Martin, A. and McLauchlan, J. (2006) Signal peptide peptidase cleavage of GB virus B core protein is required for productive infection in vivo. Journal of Biological Chemistry, 281(39), pp. 29221-29227. (doi: 10.1074/jbc.M605373200) (PMID:16882659)

This list was generated on Sat Nov 26 19:37:31 2022 GMT.