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Bilsland, A. E. , Liu, Y., Turnbull, A., Sumpton, D., Stevenson, K., Cairney, C. J., Boyd, S. M., Roffey, J., Jenkinson, D. and Keith, W. N. (2019) A novel pyrazolopyrimidine ligand of human PGK1 and stress sensor DJ1 modulates the shelterin complex and telomere length regulation. Neoplasia, 21(9), pp. 893-907. (doi: 10.1016/j.neo.2019.07.008) (PMID:31401411) (PMCID:PMC6700475)
Cairney, C. J. et al. (2017) A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds. PLoS Genetics, 13(8), e1006942. (doi: 10.1371/journal.pgen.1006942) (PMID:28806777) (PMCID:PMC5570495)
Letsolo, B. T., Jones, R. E., Rowson, J., Grimstead, J. W., Keith, W. N. , Jenkins, G. J.S. and Baird, D. M. (2017) Extensive telomere erosion is consistent with localised clonal expansions in Barrett's metaplasia. PLoS ONE, 12(3), e0174833. (doi: 10.1371/journal.pone.0174833) (PMID:28362812) (PMCID:PMC5375150)
Soria, J.C. et al. (2016) A phase I, pharmacokinetic and pharmacodynamic study of GSK2256098, a focal adhesion kinase inhibitor, in patients with advanced solid tumors. Annals of Oncology, 27(12), pp. 2268-2274. (doi: 10.1093/annonc/mdw427) (PMID:27733373)
Jamieson, D. et al. (2016) A phase I pharmacokinetic and pharmacodynamic study of the oral mitogen-activated protein kinase kinase (MEK) inhibitor, WX-554, in patients with advanced solid tumours. European Journal of Cancer, 68, pp. 1-10. (doi: 10.1016/j.ejca.2016.08.026) (PMID:27693888)
Bilsland, A. E. , Spiliopoulou, P. and Evans, T.R. J. (2016) Virotherapy: cancer gene therapy at last? F1000Research, 5, 2105. (doi: 10.12688/f1000research.8211.1) (PMID:27635234) (PMCID:PMC5007754)
Antonia, S. J. et al. (2016) Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial. Lancet Oncology, 17(7), pp. 883-895. (doi: 10.1016/S1470-2045(16)30098-5) (PMID:27269741)
Milojkovic Kerklaan, B. et al. (2016) A phase I, dose escalation, pharmacodynamic, pharmacokinetic, and food-effect study of α2 integrin inhibitor E7820 in patients with advanced solid tumors. Investigational New Drugs, 34(3), pp. 329-337. (doi: 10.1007/s10637-016-0344-9) (PMID:27039386)
Bilsland, A. E. et al. (2015) Identification of a selective G1-phase benzimidazolone inhibitor by a senescence-targeted virtual screen using artificial neural networks. Neoplasia, 17(9), pp. 704-715. (doi: 10.1016/j.neo.2015.08.009) (PMID:26476078) (PMCID:PMC4611071)