Stepping-table gadolinium-enhanced digital subtraction MR angiography of the aorta and lower extremity arteries: preliminary experience

Meaney, J. F. M., Ridgway, J. P., Chakraverty, S., Robertson, I., Kessel, D., Radjenovic, A. , Kouwenhoven, M., Kassner, A. and Smith, M. A. (1999) Stepping-table gadolinium-enhanced digital subtraction MR angiography of the aorta and lower extremity arteries: preliminary experience. Radiology, 211(1), pp. 59-67. (doi:10.1148/radiology.211.1.r99ap1859)

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Publisher's URL: http://dx.doi.org/10.1148/radiology.211.1.r99ap1859

Abstract

PURPOSE: To compare stepping-table digital subtraction gadolinium-enhanced magnetic resonance (MR) angiography of the distal aorta and lower extremity arteries with conventional catheter digital subtraction x-ray angiography in patients with arterio-occlusive disease.<p></p> MATERIALS AND METHODS: Twenty patients underwent both conventional catheter angiography and fast three-dimensional gadolinium-enhanced MR angiography of the aorta and outflow vessels at 1.5 T; the images were acquired in three consecutive imaging locations during a single infusion of a gadolinium chelate.<p></p> RESULTS: Compared with catheter angiography, according to the findings of two blinded independent reviewers, MR angiography had sensitivities of 81% and 89% and specificities of 91% and 95%, respectively, for demonstration of insignificant (≤50%) stenosis versus significant (51%–100%) stenosis. For demonstration of occlusion, the sensitivity and specificity were 94% and 97%, respectively, by consensus. There was good interobserver correlation between the two readers overall (κ = 0.65 for reporting the degree of narrowing in all lesions; 0.86, for reporting of insignificant versus significant stenoses; and 0.928, for reporting of occluded versus patent segments).<p></p> CONCLUSION: Stepping-table digital subtraction contrast material–enhanced MR angiography has high accuracy compared with catheter angiography in patients with arterio-occlusive disease of the aorta and outflow vessels. These preliminary study results suggest that this technique may ultimately provide a safe, noninvasive, and cost-effective alternative to catheter angiography.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Radjenovic, Dr Aleksandra
Authors: Meaney, J. F. M., Ridgway, J. P., Chakraverty, S., Robertson, I., Kessel, D., Radjenovic, A., Kouwenhoven, M., Kassner, A., and Smith, M. A.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Radiology
Publisher:Radiological Society of North America
ISSN:0033-8419
ISSN (Online):1527-1315

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