Maredia, N., Radjenovic, A. , Kozerke, S., Larghat, A., Greenwood, J. P. and Plein, S. (2010) Effect of improving spatial or temporal resolution on image quality and quantitative perfusion assessment with k-t SENSE acceleration in first-pass CMR myocardial perfusion imaging. Magnetic Resonance in Medicine, 64(6), pp. 1616-1624. (doi: 10.1002/mrm.22493)
|
Text
97185.pdf - Published Version 327kB |
Publisher's URL: http://dx.doi.org/10.1002/mrm.22493
Abstract
k-t Sensitivity-encoded (k-t SENSE) acceleration has been used to improve spatial resolution, temporal resolution, and slice coverage in first-pass cardiac magnetic resonance myocardial perfusion imaging. This study compares the effect of investing the speed-up afforded by k-t SENSE acceleration in spatial or temporal resolution. Ten healthy volunteers underwent adenosine stress myocardial perfusion imaging using four saturation-recovery gradient echo perfusion sequences: a reference sequence accelerated by sensitivity encoding (SENSE), and three k-t SENSE–accelerated sequences with higher spatial resolution (“k-t High”), shorter acquisition window (“k-t Fast”), or a shared increase in both parameters (“k-t Hybrid”) relative to the reference. Dark-rim artifacts and image quality were analyzed. Semiquantitative myocardial perfusion reserve index (MPRI) and Fermi-derived quantitative MPR were also calculated. The k-t Hybrid sequence produced highest image quality scores at rest (P = 0.015). Rim artifact thickness and extent were lowest using k-t High and k-t Hybrid sequences (P < 0.001). There were no significant differences in MPRI and MPR values derived by each sequence. Maximizing spatial resolution by k-t SENSE acceleration produces the greatest reduction in dark rim artifact. There is good agreement between k-t SENSE and standard acquisition methods for semiquantitative and fully quantitative myocardial perfusion analysis.
Item Type: | Articles |
---|---|
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Radjenovic, Dr Aleksandra |
Authors: | Maredia, N., Radjenovic, A., Kozerke, S., Larghat, A., Greenwood, J. P., and Plein, S. |
College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
Journal Name: | Magnetic Resonance in Medicine |
Publisher: | Wiley |
ISSN: | 0740-3194 |
ISSN (Online): | 1522-2594 |
Copyright Holders: | Copyright © 2010 Wiley-Liss, Inc. |
First Published: | First published in Magnetic Resonance in Medicine 64(6):1616-1624 |
Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
University Staff: Request a correction | Enlighten Editors: Update this record