Curtis, A. S. and Tsimbouri, P. M. (2014) Epigenesis: roles of nanotopography, nanoforces and nanovibration. Expert Review of Medical Devices, 11(4), pp. 417-423. (doi: 10.1586/17434440.2014.916205)
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Abstract
We consider three biophysical factors operating at the nanoscale which can affect gene expression, and thus, differentiation, in cultured mammalian cells. These factors are nanovibration, nanoforces and the local nanotopography. Work supporting these conclusions is reviewed. It is argued that stirring of the medium close to the cells cannot contribute to the effects. It is suggested that the three factors interact. Possible pathways by which this could occur are outlined.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Curtis, Professor Adam and Tsimbouri, Dr Monica |
Authors: | Curtis, A. S., and Tsimbouri, P. M. |
College/School: | College of Medical Veterinary and Life Sciences > School of Molecular Biosciences |
Journal Name: | Expert Review of Medical Devices |
Publisher: | Expert Reviews Ltd. |
ISSN: | 1743-4440 |
ISSN (Online): | 1745-2422 |
Related URLs: |
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