New Compound Having Multivalent Binding Capacity for Protein and Comprising Oligosaccharide Moieties Linked to a Dendrimer, Useful For Detecting Cholera Toxin and Treating Intoxication With Bacterial Toxin and Autoimmune Neuropathy

University of Rotterdam Erasmus Cent Medical (2009) New Compound Having Multivalent Binding Capacity for Protein and Comprising Oligosaccharide Moieties Linked to a Dendrimer, Useful For Detecting Cholera Toxin and Treating Intoxication With Bacterial Toxin and Autoimmune Neuropathy. .

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Abstract

The invention relates to oligosaccharide compositions having affinity for proteins and the medical or biotechnological use of such compositions. The invention provides a composition having multivalent binding capacity for a protein comprising at least two oligosaccharide moieties linked to a dendrimer, having multivalent binding capacity for a bacterial toxin, preferably an AB5 toxin.

Item Type:Patents
Additional Information:Patent Number: WO2009005353-A1
Status:Published
Glasgow Author(s) Enlighten ID:Liskamp, Professor Robert
Authors: Endzt, H.P., Van Belkum, A.F., Jacobs, B.C., Van Beek, T., Visser, G., Zuilhof, J.T., Pieters, R.J., Branderhorst, H.M., and Liskamp, R.M.J.
College/School:College of Science and Engineering > School of Chemistry
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