Zang, H.-Y., Ruiz de la Oliva, A., Miras, H. N. , Long, D.-L. , McBurney, R. T. and Cronin, L. (2014) Discovery of gigantic molecular nanostructures using a flow reaction array as a search engine. Nature Communications, 5, pp. 1-8. (doi: 10.1038/ncomms4715)
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Abstract
The discovery of gigantic molecular nanostructures like coordination and polyoxometalate clusters is extremely time-consuming since a vast combinatorial space needs to be searched, and even a systematic and exhaustive exploration of the available synthetic parameters relies on a great deal of serendipity. Here we present a synthetic methodology that combines a flow reaction array and algorithmic control to give a chemical ‘real-space’ search engine leading to the discovery and isolation of a range of new molecular nanoclusters based on [Mo2O2S2]2þ-based building blocks with either fourfold (C4) or fivefold (C5) symmetry templates and linkers. This engine leads us to isolate six new nanoscale cluster compounds: 1, {Mo10(C5)}; 2, {Mo14(C4)4(C5)2}; 3, {Mo60(C4)10}; 4, {Mo48(C4)6}; 5, {Mo34(C4)4}; 6, {Mo18(C4)9}; in only 200 automated experiments from a parameter space spanning ~ 5 million possible combinations.
Item Type: | Articles |
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Keywords: | Chemical sciences; Inorganic chemistry; Materials science; Nanotechnology |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Moiras, Professor Haralampos and Long, Dr Deliang and Cronin, Professor Lee |
Authors: | Zang, H.-Y., Ruiz de la Oliva, A., Miras, H. N., Long, D.-L., McBurney, R. T., and Cronin, L. |
Subjects: | Q Science > QD Chemistry |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Nature Communications |
Publisher: | Nature Publishing Group |
ISSN: | 2041-1723 |
ISSN (Online): | 2041-1723 |
Copyright Holders: | Copyright © 2014 Macmillan Publishers Limited |
First Published: | First published in Nature Communications 5(3715):1-8 |
Publisher Policy: | Reproduced under a Creative Commons License |
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