Vitamin D in the general population of young adults with autism in the Faroe Islands

Kocovska, E. et al. (2014) Vitamin D in the general population of young adults with autism in the Faroe Islands. Journal of Autism and Developmental Disorders, 44(12), pp. 2996-3005. (doi: 10.1007/s10803-014-2155-1) (PMID:24927807) (PMCID:PMC4221602)

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Abstract

Vitamin D deficiency has been proposed as a possible risk factor for developing autism spectrum disorder (ASD). 25-Hydroxyvitamin D3 (25(OH)D3) levels were examined in a cross-sectional population-based study in the Faroe Islands. The case group consisting of a total population cohort of 40 individuals with ASD (aged 15–24 years) had significantly lower 25(OH)D3 than their 62 typically-developing siblings and their 77 parents, and also significantly lower than 40 healthy age and gender matched comparisons. There was a trend for males having lower 25(OH)D3 than females. Effects of age, month/season of birth, IQ, various subcategories of ASD and Autism Diagnostic Observation Schedule score were also investigated, however, no association was found. The very low 25(OH)D3 in the ASD group suggests some underlying pathogenic mechanism.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Minnis, Professor Helen and Kocovska, Mrs Eva and Gillberg, Professor Christopher
Authors: Kocovska, E., Andorsdottir, G., Weihe, P., Halling, J., Fernell, E., Stora, T., Biskupsto, R., Gillberg, I. C., Shea, R., Billstedt, E., Minnis, H., Bourgeron, T., and Gillberg, C.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Mental Health and Wellbeing
Journal Name:Journal of Autism and Developmental Disorders
Publisher:Springer US
ISSN:0162-3257
ISSN (Online):1533-4406
Published Online:14 June 2014
Copyright Holders:Copyright © 2014 The Authors
First Published:First published in Journal of Autism and Developmental Disorders 2014
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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