Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

Naylor, S. W., Flockhart, A., Nart, P., Smith, D. G.E., Huntley, J., Gally, D. L. and Low, J. C. (2007) Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain. Applied and Environmental Microbiology, 73(11), pp. 3765-3767. (doi: 10.1128/AEM.02670-06)

Abstract

Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Smith, Professor David
• Authors: Naylor, S. W., Flockhart, A., Nart, P., Smith, D. G.E., Huntley, J., Gally, D. L., and Low, J. C.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity
• Journal Name: Applied and Environmental Microbiology
• Publisher: American Society for Microbiology
• ISSN: 0099-2240
• ISSN (Online): 1098-5336