Ultrasound assisted particle and cell manipulation on-chip

Mulvana, H. , Cochran, S. and Hill, M. (2013) Ultrasound assisted particle and cell manipulation on-chip. Advanced Drug Delivery Reviews, 65(11-12), pp. 1600-1610. (doi: 10.1016/j.addr.2013.07.016)

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Abstract

Ultrasonic fields are able to exert forces on cells and other micron-scale particles, including microbubbles. The technology is compatible with existing lab-on-chip techniques and is complementary to many alternative manipulation approaches due to its ability to handle many cells simultaneously over extended length scales. This paper provides an overview of the physical principles underlying ultrasonic manipulation, discusses the biological effects relevant to its use with cells, and describes emerging applications that are of interest in the field of drug development and delivery on-chip.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cochran, Professor Sandy and Mulvana, Dr Helen
Authors: Mulvana, H., Cochran, S., and Hill, M.
College/School:College of Science and Engineering > School of Engineering > Systems Power and Energy
Journal Name:Advanced Drug Delivery Reviews
ISSN:0169-409X
ISSN (Online):1872-8294

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