O’Brien, M.A. and Jackson, M. (2012) Vitamin D and the immune system: beyond rickets. Veterinary Journal, 194(1), pp. 27-33. (doi: 10.1016/j.tvjl.2012.05.022)
Full text not currently available from Enlighten.
Publisher's URL: http://dx.doi.org/10.1016/j.tvjl.2012.05.022
Abstract
In addition to its essential role in calcium homeostasis and bone metabolism, vitamin D has a diverse range of biological actions, including induction of cell differentiation, inhibition of cell growth, immunomodulation and control of hormonal systems. Vitamin D plays an immunoregulatory role in both the innate and adaptive immune systems. The active metabolite of the vitamin D endocrine system, 1,25-dihydroxyvitamin D (calcitriol), exerts pleiotropic effects through its interaction with the vitamin D receptor. Low vitamin D status in humans has been implicated in the etiology of neoplasia, autoimmune disease, cardiovascular disorders and infectious diseases. This review focuses on vitamin D and its effects on immune function, particularly in humans, with the aim to encourage further exploration in the veterinary field.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Jackson, Dr Mark |
| Authors: | O’Brien, M.A., and Jackson, M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
| Journal Name: | Veterinary Journal |
| Publisher: | Elsevier Ltd |
| ISSN: | 1090-0233 |
| ISSN (Online): | 1532-2971 |
University Staff: Request a correction | Enlighten Editors: Update this record
Deposit and Record Details
Deposit and Record Details