Thapar, A., Hammerton, G., Colllishaw, S., Potter, R., Rice, F., Harold, G., Craddock, N., Thapar, A. and Smith, D. (2014) Detecting recurrent major depressive disorder within primary care rapidly and reliably using short questionnaire measures. British Journal of General Practice, 64(618), e31-e37. (doi: 10.3399/bjgp14X676438)
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Publisher's URL: http://bjgp.org/content/64/618/e31.abstract
Abstract
<br>Background: Major depressive disorder (MDD) is often a chronic disorder with relapses usually detected and managed in primary care using a validated depression symptom questionnaire. However, for individuals with recurrent depression the choice of which questionnaire to use and whether a shorter measure could suffice is not established.</br> <br>Aim: To compare the nine-item Patient Health Questionnaire (PHQ-9), the Beck Depression Inventory, and the Hospital Anxiety and Depression Scale against shorter PHQ-derived measures for detecting episodes of DSM-IV major depression in primary care patients with recurrent MDD.</br> <br>Design and setting: Diagnostic accuracy study of adults with recurrent depression in primary care predominantly from Wales</br> <br>Method: Scores on each of the depression questionnaire measures were compared with the results of a semi-structured clinical diagnostic interview using Receiver Operating Characteristic curve analysis for 337 adults with recurrent MDD.</br> <br>Results: Concurrent questionnaire and interview data were available for 272 participants. The one-month prevalence rate of depression was 22.2%. The area under the curve (AUC) and positive predictive value (PPV) at the derived optimal cut-off value for the three longer questionnaires were comparable (AUC = 0.86–0.90, PPV = 49.4–58.4%) but the AUC for the PHQ-9 was significantly greater than for the PHQ-2. However, by supplementing the PHQ-2 score with items on problems concentrating and feeling slowed down or restless, the AUC (0.91) and the PPV (55.3%) were comparable with those for the PHQ-9.</br>
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Smith, Professor Daniel |
Authors: | Thapar, A., Hammerton, G., Colllishaw, S., Potter, R., Rice, F., Harold, G., Craddock, N., Thapar, A., and Smith, D. |
College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Mental Health and Wellbeing |
Journal Name: | British Journal of General Practice |
ISSN: | 0960-1643 |
ISSN (Online): | 1478-5242 |
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