Wells, C.A., Mosbergen, R., Korn, O., Choi, J., Seidenman, N., Matigian, N.A., Vitale, A.M. and Shepherd, J. (2013) Stemformatics: visualisation and sharing of stem cell gene expression. Stem Cell Research, 10(3), pp. 387-95. (doi: 10.1016/j.scr.2012.12.003)
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Abstract
Genome-scale technologies are increasingly adopted by the stem cell research community, because of the potential to uncover the molecular events most informative about a stem cell state. These technologies also present enormous challenges around the sharing and visualisation of data derived from different laboratories or under different experimental conditions. Stemformatics is an easy to use, publicly accessible portal that hosts a large collection of exemplar stem cell data. It provides fast visualisation of gene expression across a range of mouse and human datasets, with transparent links back to the original studies. One difficulty in the analysis of stem cell signatures is the paucity of public pathways/gene lists relevant to stem cell or developmental biology. Stemformatics provides a simple mechanism to create, share and analyse gene sets, providing a repository of community-annotated stem cell gene lists that are informative about pathways, lineage commitment, and common technical artefacts. Stemformatics can be accessed at stemformatics.org.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Wells, Dr Christine |
| Authors: | Wells, C.A., Mosbergen, R., Korn, O., Choi, J., Seidenman, N., Matigian, N.A., Vitale, A.M., and Shepherd, J. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Research Group: | Wells |
| Journal Name: | Stem Cell Research |
| ISSN: | 1873-5061 |
| Related URLs: |
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