Maurer-Stroh, S., Dickens, N.J. , Hughes-Davies, L., Kouzarides, T., Eisenhaber, F. and Ponting, C.P. (2003) The Tudor domain 'royal family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Trends in Biochemical Sciences, 28(2), pp. 69-74. (doi: 10.1016/S0968-0004(03)00004-5)
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Abstract
We have identified a family of 'Agenet' domains that are plant-specific homologs of Tudor domains. This finding has been extended, using a combination of sequence- and structure-dependent approaches, to show that the three beta-stranded core regions of Tudor, PWWP, chromatin-binding (Chromo) and MBT domains are homologous because they originate from a common ancestor. In addition, we have revealed pairs of tandem repeats in the fragile X mental retardation protein (FMRP) family that are also members of this Tudor domain 'Royal Family'.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Dickens, Dr Nicholas |
| Authors: | Maurer-Stroh, S., Dickens, N.J., Hughes-Davies, L., Kouzarides, T., Eisenhaber, F., and Ponting, C.P. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Trends in Biochemical Sciences |
| Publisher: | Elsevier (Cell Press) |
| ISSN: | 0968-0004 |
| ISSN (Online): | 1362-4326 |
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