Vasiev, I., Greer, A.I.M. , Khokhar, A.Z., Stormonth-Darling, J. , Tanner, K.E. and Gadegaard, N. (2013) Self-folding nano- and micropatterned hydrogel tissue engineering scaffolds by single step photolithographic process. Microelectronic Engineering, 108, pp. 76-81. (doi: 10.1016/j.mee.2013.04.003)
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Abstract
Current progress in tissue engineering is focused on the creation of environments in which cultures of relevant cells can adhere, grow and form functional tissue. We propose a method for controlled chemical and topographical cues through surface patterning of self-folding hydrogel films. This provides a conversion of 2D patterning techniques into a viable method of manufacturing a 3D scaffold. While similar bilayers have previously been demonstrated, here we present a faster and high throughput process for fabricating self-folding hydrogel devices incorporating controllable surface nanotopographies by serial hot embossing of sacrificial layers and photolithography.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Tanner, Professor Kathleen and Khokhar, Dr Ali and Stormonth-Darling, Mr John and Greer, Mr Andrew and Gadegaard, Professor Nikolaj |
| Authors: | Vasiev, I., Greer, A.I.M., Khokhar, A.Z., Stormonth-Darling, J., Tanner, K.E., and Gadegaard, N. |
| College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Journal Name: | Microelectronic Engineering |
| Publisher: | Elsevier |
| ISSN: | 0167-9317 |
| ISSN (Online): | 1873-5568 |
| Copyright Holders: | Copyright © 2013 Elsevier B.V. |
| First Published: | First published in Microelectronic Engineering 108:76-81 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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