Long-term follow-up of cognitive function and activities of daily living in older people: a feasibility study in the PROSPER cohort

Kerr, G.D., Robertson, M. and Stott, D.J. (2011) Long-term follow-up of cognitive function and activities of daily living in older people: a feasibility study in the PROSPER cohort. Open Clinical Trials Journal, 3(1), pp. 6-12. (doi: 10.2174/1876821001103010006)

Abstract

<p>Background: The Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) considered the benefits of pravastatin therapy and provided insights into cognitive decline/disability in older people but follow-up was short.</p> <p>Methods: We performed a feasibility study of 300 PROSPER recruits, 7 years after the trial finished. The subject’s general practitioner provided basic follow-up data. Telephone contact with participants established cognition/functional level. Relatives of those unsuitable for contact were asked to complete postal questionnaires.</p> <p>Results: Of 300 participants we established 132 were alive, 135 dead and 33 lost to follow-up. Of 132 survivors data were obtained for 78 participants by telephone, 10 participants with GP diagnosis of dementia, and 3 participants whose relative provided information. Therefore cognitive function was determined in 69% of survivors and functional ability in 61%.</p> <p>Conclusions: It was feasible to perform long-term follow-up of cognition/functional ability in the majority of survivors from a large randomised controlled trial.</p>

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Stott J, Professor David
• Authors: Kerr, G.D., Robertson, M., and Stott, D.J.
• College/School: College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
• Journal Name: Open Clinical Trials Journal
• Publisher: Bentham Open
• ISSN: 1876-8210
• Copyright Holders: Copyright © 2011 The Authors
• First Published: First published in Open Clinical Trials Journal 3(1):6-12
• Publisher Policy: Reproduced under a Creative Commons License