Approaches to the synthesis of ureapeptoid peptidomimetics

Kruijtzer, J.A.W., Lefeber, D.J. and Liskamp, R.M.J. (1997) Approaches to the synthesis of ureapeptoid peptidomimetics. Tetrahedron Letters, 38(30), pp. 5335-5338. (doi: 10.1016/S0040-4039(97)01166-0)

Abstract

Ureapeptoid peptidomimetics can be composed from Boc-protected N-substituted ethylenediamines. The best approach is to synthesize these from chloroacetonitrile followed by conversion to the corresponding crystalline p-nitrophenyl carbamates in order to prepare the ureapeptoids.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Liskamp, Professor Robert
• Authors: Kruijtzer, J.A.W., Lefeber, D.J., and Liskamp, R.M.J.
• College/School: College of Science and Engineering > School of Chemistry
• Journal Name: Tetrahedron Letters
• ISSN: 0040-4039