Boeijen, A. and Liskamp, R.M.J. (1998) Sequencing of peptoid peptidomimetics by Edman degradation. Tetrahedron Letters, 39(21), pp. 3589-3592. (doi: 10.1016/S0040-4039(98)00556-5)
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Abstract
The direct identification of resin-bound peptoid peptidomimetics by sequencing is described. The N-terminus of the peptoid was treated with phenyl isothiocyanate, after which the N-terminal peptoid residue was cleaved from the resin as its thiohydantoin derivative. For deduction of the peptoid sequence, the HPLC retention times of the obtained thiohydantoins were compared to those of independently prepared reference thiohydantoins.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Liskamp, Professor Robert |
| Authors: | Boeijen, A., and Liskamp, R.M.J. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Tetrahedron Letters |
| ISSN: | 0040-4039 |
| ISSN (Online): | 1873-3581 |
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