Reichwein, J.F., Versluis, C. and Liskamp, R.M.J. (2000) Synthesis of cyclic peptides by ring-closing metathesis. Journal of Organic Chemistry, 65(19), pp. 6187-6195. (doi: 10.1021/jo000759t)
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Abstract
The synthesis of a series of “amide to amide” cyclized peptides by ring-closing metathesis (RCM) as well as a convenient synthesis for the linear precursors is described. In addition, the influence of the length of the alkene substituents and the influence of the peptide sequence is investigated, leading to a set of general rules to obtain “amide to amide” cyclized peptides by RCM.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Liskamp, Professor Robert |
| Authors: | Reichwein, J.F., Versluis, C., and Liskamp, R.M.J. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Journal of Organic Chemistry |
| ISSN: | 0022-3263 |
| ISSN (Online): | 1520-6904 |
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