Rijkers, D.T.S., van Vugt, H.H.R., Jacobs, H.J.F. and Liskamp, R.M.J. (2002) A convenient synthesis of azido peptides by post-assembly diazo transfer on the solid phase applicable to large peptides. Tetrahedron Letters, 43(20), pp. 3657-3660. (doi: 10.1016/S0040-4039(02)00629-9)
Full text not currently available from Enlighten.
Abstract
An efficient method for the conversion of solid phase bound peptide amines into azides by a diazo transfer using triflyl azide in the presence of divalent copper ions is described. α-Azido acids and azido peptides—up to 30 amino acids in length—are obtained in good yields and high purities after cleavage from the solid support.
Item Type: | Articles |
---|---|
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Liskamp, Professor Robert |
Authors: | Rijkers, D.T.S., van Vugt, H.H.R., Jacobs, H.J.F., and Liskamp, R.M.J. |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Tetrahedron Letters |
ISSN: | 0040-4039 |
ISSN (Online): | 1873-3581 |
University Staff: Request a correction | Enlighten Editors: Update this record