Cantini, M. , Gonzalez-Garcia, C., Llopis-Hernandez, V. and Salmerón-Sánchez, M. (2012) Material-driven fibronectin fibrillogenesis. In: Horbett, T., Brash, B. and Norde, N. (eds.) Proteins at Interfaces III State of the Art 2012. Series: ACS symposium series (1120). American Chemical Society: Washington DC, VA, USA, pp. 471-496. (doi: 10.1021/bk-2012-1120.ch022)
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Publisher's URL: http://dx.doi.org/10.1021/bk-2012-1120.ch022
Abstract
Material-driven fibronectin fibrillogenesis is a novel route to engineer the network structure and biological activity of fibronectin fibrillar matrices in analogy with their physiological cell-mediated assembly. We identify specific surface chemistries that promote the cell-free formation of physiological-like fibronectin fibrils in a time- and concentration-dependent process. Our most recent and relevant results, reviewed in the chapter, demonstrate the role of this material-induced fibrillogenesis in cell adhesion, extracellular matrix organization and degradation, and cell differentiation.
Item Type: | Book Sections |
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Status: | Published |
Glasgow Author(s) Enlighten ID: | Salmeron-Sanchez, Professor Manuel and Gonzalez Garcia, Dr Cristina and Llopis-Hernandez, Dr Virginia and Cantini, Dr Marco |
Authors: | Cantini, M., Gonzalez-Garcia, C., Llopis-Hernandez, V., and Salmerón-Sánchez, M. |
College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
Publisher: | American Chemical Society |
ISSN: | 0097-6156 |
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