Gemmell, N. R., McCarthy, A., Liu, B., Tanner, M.G., Dorenbos, S.D., Zwiller, V., Patterson, M.S., Buller, G.S., Wilson, B.C. and Hadfield, R.H. (2013) Singlet oxygen luminescence detection with a fiber-coupled superconducting nanowire single-photon detector. Optics Express, 21(4), pp. 5005-5013. (doi: 10.1364/OE.21.005005)
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Abstract
Direct monitoring of singlet oxygen (1O2) luminescence is a particularly challenging infrared photodetection problem. 1O2, an excited state of the oxygen molecule, is a crucial intermediate in many biological processes. We employ a low noise superconducting nanowire single-photon detector to record 1O2 luminescence at 1270 nm wavelength from a model photosensitizer (Rose Bengal) in solution. Narrow band spectral filtering and chemical quenching is used to verify the 1O2 signal, and lifetime evolution with the addition of protein is studied. Furthermore, we demonstrate the detection of 1O2 luminescence through a single optical fiber, a marked advance for dose monitoring in clinical treatments such as photodynamic therapy.
Item Type: | Articles |
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Additional Information: | This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/OE.21.005005. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law. |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Gemmell, Mr Nathan and Hadfield, Professor Robert and Tanner, Dr Michael |
Authors: | Gemmell, N. R., McCarthy, A., Liu, B., Tanner, M.G., Dorenbos, S.D., Zwiller, V., Patterson, M.S., Buller, G.S., Wilson, B.C., and Hadfield, R.H. |
College/School: | College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering |
Journal Name: | Optics Express |
Publisher: | Optical Society of America |
ISSN: | 1094-4087 |
Published Online: | 21 February 2013 |
Copyright Holders: | Copyright © 2013 Optical Society of America |
First Published: | First published in Optics Express 21(4):5005-5013 |
Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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