Singlet oxygen luminescence detection with a fiber-coupled superconducting nanowire single-photon detector

Gemmell, N. R., McCarthy, A., Liu, B., Tanner, M.G., Dorenbos, S.D., Zwiller, V., Patterson, M.S., Buller, G.S., Wilson, B.C. and Hadfield, R.H. (2013) Singlet oxygen luminescence detection with a fiber-coupled superconducting nanowire single-photon detector. Optics Express, 21(4), pp. 5005-5013. (doi:10.1364/OE.21.005005)

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Abstract

Direct monitoring of singlet oxygen (1O2) luminescence is a particularly challenging infrared photodetection problem. 1O2, an excited state of the oxygen molecule, is a crucial intermediate in many biological processes. We employ a low noise superconducting nanowire single-photon detector to record 1O2 luminescence at 1270 nm wavelength from a model photosensitizer (Rose Bengal) in solution. Narrow band spectral filtering and chemical quenching is used to verify the 1O2 signal, and lifetime evolution with the addition of protein is studied. Furthermore, we demonstrate the detection of 1O2 luminescence through a single optical fiber, a marked advance for dose monitoring in clinical treatments such as photodynamic therapy.

Item Type:Articles
Additional Information:This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/OE.21.005005. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Tanner, Dr Michael and Gemmell, Mr Nathan and Hadfield, Professor Robert
Authors: Gemmell, N. R., McCarthy, A., Liu, B., Tanner, M.G., Dorenbos, S.D., Zwiller, V., Patterson, M.S., Buller, G.S., Wilson, B.C., and Hadfield, R.H.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
Journal Name:Optics Express
Publisher:Optical Society of America
ISSN:1094-4087
Published Online:21 February 2013
Copyright Holders:Copyright © 2013 Optical Society of America
First Published:First published in Optics Express 21(4):5005-5013
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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