Byrne, S.J., Corr, S.A., Rakovich, T.Y., Gun'ko, Y.K., Rakovich, Y.P., Donegan, J.F., Mitchell, S. and Volkov, Y. (2006) Optimisation of the synthesis and modification of CdTe quantum dots for enhanced live cell imaging. Journal of Materials Chemistry, 16(28), pp. 2896-2902. (doi: 10.1039/B605333E)
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Abstract
We report the preparation and luminescence enhancement of thioglycolic acid (TGA) stabilised CdTe quantum dots (QDs) for use as live cell imaging tools in THP-1 macrophage cells. Short irradiating times utilising a high powered Hg lamp resulted in increases in luminescence efficiencies of up to similar40% and permit significantly enhanced live imaging of the THP-1 cellular components. It was found that the TGA-stabilised QDs traverse the cell membrane{,} illuminating the cytoplasm and decorating the nuclear membrane. These studies highlight the potential use of photoetched CdTe QDs as probes for specific labelling.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Corr, Professor Serena |
| Authors: | Byrne, S.J., Corr, S.A., Rakovich, T.Y., Gun'ko, Y.K., Rakovich, Y.P., Donegan, J.F., Mitchell, S., and Volkov, Y. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Journal of Materials Chemistry |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 0959-9428 |
| ISSN (Online): | 1364-5501 |
| Published Online: | 12 June 2006 |
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