MacGregor, A.N., Stott, D.I. and Kusel, J.R. (1985) Lectin binding to glycoproteins in the surface membrane of Schistosoma mansoni. Molecular and Biochemical Parasitology, 16(2), pp. 163-172. (doi: 10.1016/0166-6851(85)90084-2)
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Abstract
A number of lectins were assessed for their ability to bind to glycoproteins in the surface membrane of Schistosoma mansoni. The membrane polypeptides were separated by SDS-PAGE and the glycoproteins visualised by incubating the gel with radio-iodinated lectin followed by autoradiography. Most of the individual lectins bound to a variety of glycoproteins but peanut agglutinin and Dolichos biflorus agglutinin bound preferentially to a single glycoprotein of apparent molecular weight 170 000. This glycoprotein was subsequently shown to be exposed at the surface of the parasite and localised at the tubercles.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Stott I, Professor David |
Authors: | MacGregor, A.N., Stott, D.I., and Kusel, J.R. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Molecular and Biochemical Parasitology |
Publisher: | Elsevier BV |
ISSN: | 0166-6851 |
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