Sutherland, A. and Cant, A. (2012) Asymmetric synthesis of pipecolic acid and derivatives. Synthesis, 44(13), pp. 1935-1950. (doi: 10.1055/s-0031-1289767)
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Abstract
The nonproteinogenic α-amino acid, l-pipecolic acid and its derivatives are components of a wide range of pharmacologically active compounds. The significant biological activity of these compounds has resulted in the development of many synthetic approaches for their preparation. This review highlights these key methods as well as the application of these compounds for the preparation of enzyme inhibitors, conformationally restricted building blocks and peptidomimetics.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Cant, Mr Alastair and Sutherland, Professor Andrew |
| Authors: | Sutherland, A., and Cant, A. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Synthesis |
| Publisher: | Georg Thieme Verlag |
| ISSN: | 0039-7881 |
| ISSN (Online): | 1437-210X |
| Published Online: | 25 May 2012 |
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