Ford, I. (1991) Angina clinical trial methodology. Postgraduate Medical Journal, 67(Sup 3), S2-S8.
Full text not currently available from Enlighten.
Abstract
This paper reviews the general structure of clinical trials with special reference to those in the area of angina. In particular, aspects of experimental design in exercise testing, ambulatory monitoring and mortality studies are examined critically. Parallel group and crossover studies are compared and contrasted. Sensitivity analysis of the power of any proposed trial is recommended, and problems that can arise in the area of event rate estimation are illustrated. Additional problems associated with trials involving combination therapies, trials with no placebo group and regression to the mean are discussed.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Ford, Professor Ian |
| Authors: | Ford, I. |
| Subjects: | R Medicine > R Medicine (General) |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Robertson Centre |
| Journal Name: | Postgraduate Medical Journal |
| ISSN: | 0032-5473 |
University Staff: Request a correction | Enlighten Editors: Update this record
Deposit and Record Details
Deposit and Record Details