Primary intracranial leiomyosarcoma: a case report and review of the literature

Mathieson, C.S., St George, E.J., Stewart, W. , Sastry, J. and Jamal, S. (2009) Primary intracranial leiomyosarcoma: a case report and review of the literature. Child's Nervous System, 25(8), pp. 1013-1017. (doi: 10.1007/s00381-009-0845-3)

Abstract

Introduction<p></p> Malignant tumours of the central nervous system (CNS) represent the second most common cancer type in the paediatric population of developed countries, and mortality caused by CNS tumours is the highest among paediatric cancers. Tumours of mesenchymal origin occurring either as primary or secondary lesions of the central nervous system are very rare in children. This paper describes the case of a 5-year-old non-immunocompromised male who presented with a right frontal primary intracranial leiomyosarcoma associated with large subdural collections.<p></p> Discussion and conclusion<p></p> Following surgical excision and adjuvant chemoradiotherapy, the patient has remained disease-free for 18 months. The literature is reviewed and the possible association of the chronic subdurals to the later development of the leiomyosarcoma explored.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Sastry, Dr Jairam and Stewart, Dr William
• Authors: Mathieson, C.S., St George, E.J., Stewart, W., Sastry, J., and Jamal, S.
• College/School: College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Child's Nervous System
• ISSN: 0256-7040
• ISSN (Online): 1433-0350