Bulleid, N.J. (2012) Solving the mystery of procollagen chain selectivity. Nature Structural and Molecular Biology, 19(10), pp. 977-978. (doi: 10.1038/nsmb.2397)
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Abstract
The recently solved crystal structure of the procollagen C propeptide reveals the basis for chain selectivity as well as an unexpected asymmetry to this homotrimeric molecule. In addition, mapping disease-causing mutations to the structure demonstrates clear correlation between severity of disease and mutation location.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Bulleid, Professor Neil |
Authors: | Bulleid, N.J. |
College/School: | College of Medical Veterinary and Life Sciences > School of Molecular Biosciences |
Journal Name: | Nature Structural and Molecular Biology |
Publisher: | Nature Publishing Group |
ISSN: | 1545-9993 |
ISSN (Online): | 1545-9985 |
Published Online: | 04 October 2012 |
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