Carotid wall motion analysis based on B-mode ultrasound images

Hopkins, W., Gao, H. , Das, S. and Long, Q. (2010) Carotid wall motion analysis based on B-mode ultrasound images. In: 6th World Congress of Biomechanics (WCB 2010), Singapore, 1-6 Aug 2010, pp. 871-874. (doi: 10.1007/978-3-642-14515-5_222)

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The aim of this study was to explore the arterial wall dynamics in an attempt to demonstrate premature atherosclerosis and arterial stiffening. Methods: A dedicated motion capture (MOCAP) framework was developed based on Matlab® using a cross correlation algorithm for block matching. Results: This study demonstrated that longitudinal and radial movements decreased according to age. 60 healthy carotids were assessed using our motion tracking algorithm. The subjects were divided into three age groups; group 1: subjects younger than 35, group 2: 35 to 50, group 3: subjects over 50. A unilateral t-test was employed to assess the relationship between groups. The hypothesis test showed that wall motion in group 1 was significantly different from group 2 and group 3 (p<0.05). It was also evident that the intima-media complex demonstrated a larger longitudinal displacement than the adventitial layer. Therefore there is shear strain within the vessel wall. Conclusion: With the development of MOCAP using Matlab®, we were able to quantify and reproduce arterial wall dynamics. We aim to implement MOCAP into the routine ultrasound examination, providing a new diagnostic parameter to improve patient management.

Item Type:Conference Proceedings
Additional Information:IFMBE Proceedings, 2010, Volume 31, Part 3, 871-874
Glasgow Author(s) Enlighten ID:Gao, Dr Hao
Authors: Hopkins, W., Gao, H., Das, S., and Long, Q.
College/School:College of Science and Engineering > School of Mathematics and Statistics > Mathematics

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