Grafton, M.W., Farrugia, L.J., Senn, H.M. and Sutherland, A. (2012) Discovery of a multi-bond forming, four-step tandem process: construction of drug-like polycyclic scaffolds. Chemical Communications, 48, pp. 7994-7996. (doi: 10.1039/c2cc33649a)
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Publisher's URL: http://dx.doi.org/10.1039/c2cc33649a
Abstract
A one-pot tandem process involving an Overman rearrangement, ring closing enyne metathesis and a hydrogen bonding directed Diels–Alder reaction has been developed for the efficient diastereoselective synthesis of functionalised amino substituted tetralin and indene ring systems.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Farrugia, Dr Louis and Senn, Dr Hans and Sutherland, Professor Andrew |
| Authors: | Grafton, M.W., Farrugia, L.J., Senn, H.M., and Sutherland, A. |
| Subjects: | Q Science > QD Chemistry |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Chemical Communications |
| Journal Abbr.: | Chem. Comm. |
| ISSN: | 1359-7345 |
| ISSN (Online): | 1364-548X |
| Published Online: | 19 June 2012 |
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