Hock, A.K. and Vousden, K.H. (2012) Tumor suppression by p53: fall of the triumvirate? Cell, 149(6), pp. 1183-1185. (doi: 10.1016/j.cell.2012.05.024)
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Publisher's URL: http://dx.doi.org/10.1016/j.cell.2012.05.024
Abstract
p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has generally been ascribed to the induction of cell-cycle arrest, apoptosis, or senescence upon stress. Li et al. challenge this dogma with evidence that all three of these programs are dispensable for p53's tumor suppressive role.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Vousden, Karen |
| Authors: | Hock, A.K., and Vousden, K.H. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Cell |
| ISSN: | 0092-8674 |
| Published Online: | 07 June 2012 |
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