Shekhar, S., Milling, S. , Jenkins, C. and MacPherson, G. (2012) Identification and phenotypic characterization of γδ T cells in rat lymph. Research in Veterinary Science, 93(1), pp. 168-171. (doi: 10.1016/j.rvsc.2011.07.014)
Full text not currently available from Enlighten.
Publisher's URL: http://dx.doi.org/10.1016/j.rvsc.2011.07.014
Abstract
γδ T cells represent an unconventional subset of T lymphocytes that are abundant in epithelial tissues and serve as an early immune defense against microbes. We have, for the first time, identified γδ T cells in steady-state thoracic duct lymph (TDL) from rats. The lymph contains γδ T cells expressing CD8 but not CD4, CD25, MHC-II or CD103. The percentage of TDL γδ T cells in rats does not change when the mesenteric lymph nodes (MLN) are surgically removed. Our data suggest that a proportion of γδ T cells migrate from the intestine into rat TDL, under steady-state conditions.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Milling, Professor Simon |
| Authors: | Shekhar, S., Milling, S., Jenkins, C., and MacPherson, G. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Research in Veterinary Science |
| Publisher: | Elsevier |
| ISSN: | 0034-5288 |
| ISSN (Online): | 1532-2661 |
| Published Online: | 20 August 2011 |
| Related URLs: |
University Staff: Request a correction | Enlighten Editors: Update this record
Altmetric
Altmetric