Formal synthesis of (+)-crocacin C

Pasqua, A.E., Ferrari, F.D., Crawford, J.J. and Marquez, R. (2012) Formal synthesis of (+)-crocacin C. Tetrahedron Letters, 53(16), pp. 2114-2116. (doi: 10.1016/j.tetlet.2012.02.049)

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Publisher's URL: http://dx.doi.org/10.1016/j.tetlet.2012.02.049

Abstract

The formal synthesis of (+)-crocacin C is reported. The approach described takes advantage of a highly regioselective epoxide cuprate addition and a diastereoselective Overman rearrangement. The synthesis is practical and amenable to scale up.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Marquez, Dr Rudi and Ferrari, Mr Frank
Authors: Pasqua, A.E., Ferrari, F.D., Crawford, J.J., and Marquez, R.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Tetrahedron Letters
ISSN:0040-4039
Published Online:18 February 2012

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