Cant, A., Bhalla, R., Pimlott, S.L. and Sutherland, A. (2012) Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides. Chemical Communications, 48(33), pp. 3993-3995. (doi: 10.1039/c2cc30956d)
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Publisher's URL: http://dx.doi.org/10.1039/C2CC30956D
Abstract
A fast and efficient nickel-catalysed iodination reaction of aryl and heteroaryl bromides has been developed. The transformation was found to be general for a wide range of substrates and was used for the synthesis of iodo-PK11195, an imaging agent of Alzheimer's disease and iniparib, a compound used in the treatment of breast cancer.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Pimlott, Dr Sally and Cant, Mr Alastair and Sutherland, Professor Andrew |
| Authors: | Cant, A., Bhalla, R., Pimlott, S.L., and Sutherland, A. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Chemical Communications |
| Journal Abbr.: | Chem. Comm. |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1359-7345 |
| ISSN (Online): | 1364-548X |
| Published Online: | 22 February 2012 |
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