Effect of iron limitation on the production of Streptolysin S (SLS) of Streptococcus pyogenes Group A

Memon, B.A. and Birkbeck, H. (2011) Effect of iron limitation on the production of Streptolysin S (SLS) of Streptococcus pyogenes Group A. African Journal of Microbiology Research, 5(26), pp. 4678-4681.

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Publisher's URL: http://www.academicjournals.org/ajmr/abstracts/abstracts/abstract 2011/16Nov/Memon and Birkbeck.htm

Abstract

The effect of iron on the growth of <i>Streptococcus pyogenes</i> Group A and its influence on Streptolysisn S (SLS) production was investigated. Two strains of <i>S. pyogenes</i> used in this study C203S and 55903 M were grown in iron-restricted medium. The iron chelator, (Ethylenediamindi-(o- hydroxyphenyl-acetic acid) (EDDA) was added at a concentration giving a 10-fold molar excess over Fe. Successful growth of strains of <i>S. pyogenes</i> was obtained suggesting no absolute requirement for iron in the growth and the yield of SLS was not affected by the concentration of iron in the growth medium.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Birkbeck, Professor Harry
Authors: Memon, B.A., and Birkbeck, H.
College/School:College of Medical Veterinary and Life Sciences > School of Life Sciences
Journal Name:African Journal of Microbiology Research
ISSN (Online):1996-0808

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