Copper-mediated cross-coupling of functionalized arylmagnesium reagents with functionalized alkyl and benzylic halides

Dohle, W., Lindsay, D. and Knochel, P. (2001) Copper-mediated cross-coupling of functionalized arylmagnesium reagents with functionalized alkyl and benzylic halides. Organic Letters, 3(18), pp. 2871-2873. (doi: 10.1021/ol0163272)

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Publisher's URL: http://dx.doi.org/10.1021/ol0163272

Abstract

Functionalized arylmagnesium halides, prepared via an iodine−magnesium exchange, undergo a smooth cross-coupling reaction with functionalized primary alkyl iodides and benzylic bromides in the presence of CuCN·2LiCl, either in stoichiometric (with trimethyl phosphite as an additive) or catalytic quantities.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Lindsay, Dr David
Authors: Dohle, W., Lindsay, D., and Knochel, P.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Organic Letters
Journal Abbr.:Org. Lett.
ISSN:1523-7060
ISSN (Online):1523-7052
Published Online:04 August 2001

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